5-(1-{[2-(difluoromethoxy)phenyl]methyl}-2-{[3-(2-oxopyrrolidin-1-yl)phenoxy]methyl}-1H-benzimidazol-6-yl)pyridin-2(1H)-one
P01375 — Tumor necrosis factor
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand D84
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand D84
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P01375 | n/a | 7kpa | D84 | C | 201 | e7kpaA1 | jelly-roll | TNF-like | TNF-like | TNF |
| P01375 | n/a | 7kpa | D84 | C | 201 | e7kpaB1 | jelly-roll | TNF-like | TNF-like | TNF |
| P01375 | n/a | 7kpa | D84 | C | 201 | e7kpaC1 | jelly-roll | TNF-like | TNF-like | TNF |
| P01375 | n/a | 7kpb | D84 | C | 201 | e7kpbA1 | jelly-roll | TNF-like | TNF-like | TNF |
| P01375 | n/a | 7kpb | D84 | C | 201 | e7kpbB1 | jelly-roll | TNF-like | TNF-like | TNF |
| P01375 | n/a | 7kpb | D84 | C | 201 | e7kpbC1 | jelly-roll | TNF-like | TNF-like | TNF |