4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile

P03366 — Gag-Pol polyprotein

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB08864

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB08864

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P03366	DB08864	2zd1	T27	A	557	e2zd1A5	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	2zd1	T27	A	557	e2zd1A7	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	2zd1	T27	A	557	e2zd1B2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	2ze2	T27	A	556	e2ze2A5	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	2ze2	T27	A	556	e2ze2A7	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	2ze2	T27	A	556	e2ze2B2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	3bgr	T27	A	556	e3bgrA5	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	3bgr	T27	A	556	e3bgrA7	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	3bgr	T27	A	556	e3bgrB2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	3qlh	T27	A	555	e3qlhA5	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	3qlh	T27	A	555	e3qlhA7	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	3qlh	T27	A	555	e3qlhB6	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4g1q	T27	A	601	e4g1qA5	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	4g1q	T27	A	601	e4g1qA7	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4g1q	T27	A	601	e4g1qB6	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4icl	T27	A	601	e4iclA5	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	4icl	T27	A	601	e4iclA8	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4icl	T27	A	601	e4iclB5	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4id5	T27	A	601	e4id5A5	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	4id5	T27	A	601	e4id5A8	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4id5	T27	A	601	e4id5B5	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4idk	T27	A	601	e4idkA5	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	4idk	T27	A	601	e4idkA8	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4idk	T27	A	601	e4idkB5	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4ifv	T27	A	601	e4ifvA5	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	4ifv	T27	A	601	e4ifvA8	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4ifv	T27	A	601	e4ifvB5	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4ify	T27	A	601	e4ifyA5	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	4ify	T27	A	601	e4ifyA8	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4ify	T27	A	601	e4ifyB5	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4ig3	T27	A	601	e4ig3A5	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	4ig3	T27	A	601	e4ig3A8	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4ig3	T27	A	601	e4ig3B6	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4kfb	T27	A	607	e4kfbA5	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	4kfb	T27	A	607	e4kfbA7	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	4kfb	T27	A	607	e4kfbB9	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	5cym	T27	A	601	e5cymA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	5cym	T27	A	601	e5cymA3	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	5cym	T27	A	601	e5cymB2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	5cyq	T27	A	601	e5cyqA3	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	5cyq	T27	A	601	e5cyqA4	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	5cyq	T27	A	601	e5cyqB3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	6eli	T27	A	701	e6eliA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	6eli	T27	A	701	e6eliA4	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	6eli	T27	A	701	e6eliB2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	7z2d	T27	A	601	e7z2dA3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	7z2d	T27	A	601	e7z2dA4	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	7z2d	T27	A	601	e7z2dB1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	7z2e	T27	A	601	e7z2eA1	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	7z2e	T27	A	601	e7z2eA3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	7z2e	T27	A	601	e7z2eB2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dx2	T27	A	601	e8dx2A2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dx2	T27	A	601	e8dx2A4	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	8dx2	T27	A	601	e8dx2B3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dx3	T27	A	702	e8dx3A1	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	8dx3	T27	A	702	e8dx3A2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dx3	T27	A	702	e8dx3B1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dx8	T27	A	602	e8dx8A1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dx8	T27	A	602	e8dx8A3	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	8dx8	T27	A	602	e8dx8B1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxb	T27	A	903	e8dxbA2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxb	T27	A	903	e8dxbA4	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	8dxb	T27	A	903	e8dxbB2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxe	T27	A	602	e8dxeA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxe	T27	A	602	e8dxeA2	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	8dxe	T27	A	602	e8dxeB2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxg	T27	A	602	e8dxgA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxg	T27	A	602	e8dxgA4	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	8dxg	T27	A	602	e8dxgB3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxh	T27	A	602	e8dxhA1	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	8dxh	T27	A	602	e8dxhA3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxh	T27	A	602	e8dxhB1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxi	T27	A	601	e8dxiA2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxi	T27	A	601	e8dxiA3	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	8dxi	T27	A	601	e8dxiB1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxj	T27	A	601	e8dxjA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxj	T27	A	601	e8dxjA4	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	8dxj	T27	A	601	e8dxjB1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxk	T27	A	601	e8dxkA2	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	8dxk	T27	A	601	e8dxkA4	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxk	T27	A	601	e8dxkB3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxl	T27	A	601	e8dxlA1	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	8dxl	T27	A	601	e8dxlA2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxl	T27	A	601	e8dxlB3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxm	T27	A	602	e8dxmA2	Ribonuclease H-like	RNaseH-like domain in reverse transcriptase	RNaseH-like domain in reverse transcriptase	RVT_connect
P03366	DB08864	8dxm	T27	A	602	e8dxmA3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1
P03366	DB08864	8dxm	T27	A	602	e8dxmB2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RVT_1