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P04035

HMGCR — 3-hydroxy-3-methylglutaryl-coenzyme A reductase

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Lists of molecules and drugs that interact with protein P04035
DrugDomain DataDrugBank IDPDB LigandLigand NameChEMBLPubChemInChIKey
ExploreDB00157NAI
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
CHEMBL1234616439153BOPGDPNILDQYTO-NNYOXOHSSA-N
ExploreDB00175n/a
Pravastatin
n/an/an/a
ExploreDB00227803
LOVASTATIN
CHEMBL50353232PCZOHLXUXFIOCF-BXMDZJJMSA-N
ExploreDB00439116
7-[4-(4-FLUORO-PHENYL)-5-HYDROXYMETHYL-2,6-DIISOPROPYL-PYRIDIN-3-YL]-3,5-DIHYDROXY-HEPTANOIC ACID
None5287419SRJZNZZJAOQUOF-WOJBJXKFSA-N
ExploreDB00641n/a
Simvastatin
n/an/an/a
ExploreDB01076117
7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]- 3,5-DIHYDROXY-HEPTANOIC ACID
CHEMBL148760823XUKUURHRXDUEBC-KAYWLYCHSA-N
ExploreDB01095115
(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
CHEMBL1078446155FJLGEFLZQAZZCD-MCBHFWOFSA-N
ExploreDB01098FBI
7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL] -3,5-DIHYDROXY-HEPTANOIC ACID
None5288194ZVPAUNJUMAQCNK-IAGOWNOFSA-N
ExploreDB01992COA
COENZYME A
CHEMBL121332787642RGJOEKWQDUBAIZ-IBOSZNHHSA-N
ExploreDB03169HMG
3-HYDROXY-3-METHYLGLUTARYL-COENZYME A
None131704231;5288565CABVTRNMFUVUDM-VRHQGPGLSA-I
ExploreDB03461NAP
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
CHEMBL29506957525501;5885XJLXINKUBYWONI-NNYOXOHSSA-N
ExploreDB04377MAH
3-HYDROXY-3-METHYL-GLUTARIC ACID
CHEMBL504441662NPOAOTPXWNWTSH-UHFFFAOYSA-N
ExploreDB04447DTT
2,3-DIHYDROXY-1,4-DITHIOBUTANE
CHEMBL406270439196VHJLVAABSRFDPM-IMJSIDKUSA-N
ExploreDB066932UO
Mevastatin, Compactin
CHEMBL5444064715AJLFOPYRIVGYMJ-INTXDZFKSA-N
ExploreDB08860PV9
Pitavastatin
CHEMBL12017535282452VGYFMXBACGZSIL-MCBHFWOFSA-N
ExploreDB09061P0T
cannabidiol
CHEMBL190461644019QHMBSVQNZZTUGM-ZWKOTPCHSA-N
ExploreDB14011n/a
Nabiximols
n/an/an/a
ExploreDB14546SO4
SULFATE ION
None1117QAOWNCQODCNURD-UHFFFAOYSA-L
ExploreDB14714SIM
Simvastatin acid
CHEMBL120139164718XWLXKKNPFMNSFA-HGQWONQESA-N
ExploreDB16833ADP
ADENOSINE-5'-DIPHOSPHATE
CHEMBL148306022XTWYTFMLZFPYCI-KQYNXXCUSA-N
ExploreNone114
(3R,5R)-3,5-dihydroxy-7-[(1S,2S,8S,8aR)-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]h eptanoic acid
CHEMBL503456446154BOZILQFLQYBIIY-INTXDZFKSA-N
ExploreNone3HI
(3R,5R)-7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
CHEMBL15659808225CZBPKFICAYVHHM-JWQCQUIFSA-N
ExploreNone4HI
(3R,5R)-7-[4-(benzylcarbamoyl)-2-(4-fluorophenyl)-5-(1-methylethyl)-1H-imidazol-1-yl]-3,5-dihydroxyheptanoic acid
CHEMBL48863611612975ATGOOVTXNDYCBK-FGZHOGPDSA-N
ExploreNone5HI
(3R,5R)-7-[2-(4-fluorophenyl)-4-{[(1S)-2-hydroxy-1-phenylethyl]carbamoyl}-5-(1-methylethyl)-1H-imidazol-1-yl]-3,5-dihydroxyheptanoic acid
CHEMBL48763124812713YBLASZBVZVCRFU-DNVJHFABSA-N
ExploreNone6HI
(3R,5R)-7-{2-[(4-fluorobenzyl)carbamoyl]-4-(4-fluorophenyl)-1-(1-methylethyl)-1H-imidazol-5-yl}-3,5-dihydroxyheptanoic acid
None24812714KNKKPGAQSAHIHV-FGZHOGPDSA-N
ExploreNone7HI
(3R,5R)-7-[3-(biphenyl-4-ylcarbamoyl)-2-ethyl-5,6,7,8-tetrahydrocyclohepta[b]pyrrol-1(4H)-yl]-3,5-dihydroxyheptanoic acid
None49866568OUBFNRRLNMXSKZ-JWQCQUIFSA-N
ExploreNone882
(3R,5R)-7-[5-(ANILINOCARBONYL)-3,4-BIS(4-FLUOROPHENYL)-1-ISOPROPYL-1H-PYRROL-2-YL]-3,5-DIHYDROXYHEPTANOIC ACID
CHEMBL38900211753476VZMMUQFHUUOVEM-KAYWLYCHSA-N
ExploreNone8HI
(3R,5R)-7-{3-(4-fluorophenyl)-1-(1-methylethyl)-4-phenyl-5-[(4-sulfamoylphenyl)carbamoyl]-1H-pyrrol-2-yl}-3,5-dihydroxyheptanoic acid
CHEMBL120622511763597ZBCQTJGKEZGMGJ-CLJLJLNGSA-N
ExploreNone9HI
(3R,5R)-7-{3-[(4-carbamoylphenyl)sulfamoyl]-4,5-bis(4-fluorophenyl)-2-(1-methylethyl)-1H-pyrrol-1-yl}-3,5-dihydroxyheptanoic acid
CHEMBL120742411592691IYYNBGFAAGBIAX-KAYWLYCHSA-N
ExploreNoneHR1
(3R,5R)-7-[1-(4-FLUOROPHENYL)-3-ISOPROPYL-4-OXO-5-PHENYL-4,5-DIHYDRO-3H-PYRROLO[2,3-C]QUINOLIN-2-YL]-3,5-DIHYDROXYHEPTANOIC ACID
CHEMBL120778711512591UFHOPRVARZPTSH-JWQCQUIFSA-N
ExploreNoneHR2
(3R,5R)-7-[3-(4-FLUOROPHENYL)-1-ISOPROPYL-8-OXO-7-PHENYL-1,4,5,6,7,8-HEXAHYDROPYRROLO[2,3-C]AZEPIN-2-YL]-3,5-DIHYDROXYHEPTANOIC ACID
CHEMBL52103916220139OMBVEVHRIQULKW-DNQXCXABSA-N
ExploreNoneRID
(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-4-(morpholin-4-ylsulfonyl)-3-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
CHEMBL120738511527173XLVZRBHNHHAPDT-JWQCQUIFSA-N
ExploreNoneRIE
(3R,5R)-7-[1-(4-fluorophenyl)-4-(1-methylethyl)-3-{methyl[(1R)-1-phenylethyl]carbamoyl}-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoic acid
CHEMBL120735511656602MPDDTAJMJCESGV-CTUHWIOQSA-N