Attributes
UniProt ID
Protein Name
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Ligand Name
(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
FJLGEFLZQAZZCD-MCBHFWOFSA-N
SMILES
CC(C)n1c2ccccc2c(c1C=CC(CC(CC(=O)O)O)O)c3ccc(cc3)F
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 1HWI
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Color Legend
Unassigned regionsLigand / hetero atomse1hwiA1e1hwiA2e1hwiB1e1hwiB2e1hwiC1e1hwiC2e1hwiD1e1hwiD2
ECOD domains from experimental PDB structures interacting with ligand DB01095
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P04035 | DB01095 | 115 | 1hwi | e1hwiA1 | A:587-703 |
| P04035 | DB01095 | 115 | 1hwi | e1hwiA2 | A:462-586,A:704-855 |
| P04035 | DB01095 | 115 | 1hwi | e1hwiB1 | B:587-703 |
| P04035 | DB01095 | 115 | 1hwi | e1hwiB2 | B:462-586,B:704-860 |
| P04035 | DB01095 | 115 | 1hwi | e1hwiC1 | C:587-703 |
| P04035 | DB01095 | 115 | 1hwi | e1hwiC2 | C:489-586,C:704-862 |
| P04035 | DB01095 | 115 | 1hwi | e1hwiD1 | D:587-703 |
| P04035 | DB01095 | 115 | 1hwi | e1hwiD2 | D:487-586,D:704-860 |