Attributes
UniProt ID
Protein Name
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Ligand Name
7-[4-(4-FLUORO-PHENYL)-5-HYDROXYMETHYL-2,6-DIISOPROPYL-PYRIDIN-3-YL]-3,5-DIHYDROXY-HEPTANOIC ACID
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
SRJZNZZJAOQUOF-WOJBJXKFSA-N
SMILES
CC(C)c1c(c(c(c(n1)C(C)C)COC)c2ccc(cc2)F)CCC(CC(CC(=O)O)O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 1HWJ
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Color Legend
Unassigned regionsLigand / hetero atomse1hwjA1e1hwjA2e1hwjB1e1hwjB2e1hwjC1e1hwjC2e1hwjD1e1hwjD2
ECOD domains from experimental PDB structures interacting with ligand DB00439
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P04035 | DB00439 | 116 | 1hwj | e1hwjA1 | A:587-703 |
| P04035 | DB00439 | 116 | 1hwj | e1hwjA2 | A:452-586,A:704-852 |
| P04035 | DB00439 | 116 | 1hwj | e1hwjB1 | B:587-703 |
| P04035 | DB00439 | 116 | 1hwj | e1hwjB2 | B:463-586,B:704-860 |
| P04035 | DB00439 | 116 | 1hwj | e1hwjC1 | C:587-703 |
| P04035 | DB00439 | 116 | 1hwj | e1hwjC2 | C:451-586,C:704-850 |
| P04035 | DB00439 | 116 | 1hwj | e1hwjD1 | D:587-703 |
| P04035 | DB00439 | 116 | 1hwj | e1hwjD2 | D:462-586,D:704-854 |