Attributes
UniProt ID
Protein Name
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Ligand Name
(3R,5R)-7-[2-(4-fluorophenyl)-4-{[(1S)-2-hydroxy-1-phenylethyl]carbamoyl}-5-(1-methylethyl)-1H-imidazol-1-yl]-3,5-dihydroxyheptanoic acid
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
YBLASZBVZVCRFU-DNVJHFABSA-N
SMILES
CC(C)c1c(nc(n1CCC(CC(CC(=O)O)O)O)c2ccc(cc2)F)C(=O)NC(CO)c3ccccc3
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 3CCZ
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Color Legend
Unassigned regionsLigand / hetero atomse3cczA1e3cczA2e3cczB1e3cczB2e3cczC1e3cczC2e3cczD1e3cczD2
ECOD domains from experimental PDB structures interacting with ligand 5HI
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P04035 | n/a | 5HI | 3ccz | e3cczA1 | A:570-686 |
| P04035 | n/a | 5HI | 3ccz | e3cczA2 | A:441-569,A:687-860 |
| P04035 | n/a | 5HI | 3ccz | e3cczB1 | B:576-692 |
| P04035 | n/a | 5HI | 3ccz | e3cczB2 | B:441-575,B:693-860 |
| P04035 | n/a | 5HI | 3ccz | e3cczC1 | C:587-703 |
| P04035 | n/a | 5HI | 3ccz | e3cczC2 | C:444-586,C:704-860 |
| P04035 | n/a | 5HI | 3ccz | e3cczD1 | D:576-692 |
| P04035 | n/a | 5HI | 3ccz | e3cczD2 | D:458-575,D:693-860 |