Attributes
UniProt ID
Protein Name
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Ligand Name
7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL] -3,5-DIHYDROXY-HEPTANOIC ACID
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ZVPAUNJUMAQCNK-IAGOWNOFSA-N
SMILES
CC(C)c1c(c(nc(n1)N(C)S(=O)(=O)C)c2ccc(cc2)F)CCC(CC(CC(=O)O)O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 1HWL
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse1hwlA1e1hwlA2e1hwlB1e1hwlB2e1hwlC1e1hwlC2e1hwlD1e1hwlD2
ECOD domains from experimental PDB structures interacting with ligand DB01098
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P04035 | DB01098 | FBI | 1hwl | e1hwlA1 | A:587-703 |
| P04035 | DB01098 | FBI | 1hwl | e1hwlA2 | A:450-586,A:704-849 |
| P04035 | DB01098 | FBI | 1hwl | e1hwlB1 | B:587-703 |
| P04035 | DB01098 | FBI | 1hwl | e1hwlB2 | B:463-586,B:704-860 |
| P04035 | DB01098 | FBI | 1hwl | e1hwlC1 | C:587-703 |
| P04035 | DB01098 | FBI | 1hwl | e1hwlC2 | C:463-586,C:704-860 |
| P04035 | DB01098 | FBI | 1hwl | e1hwlD1 | D:587-703 |
| P04035 | DB01098 | FBI | 1hwl | e1hwlD2 | D:479-586,D:704-860 |