Attributes
UniProt ID
Protein Name
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Ligand Name
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XJLXINKUBYWONI-NNYOXOHSSA-N
SMILES
c1cc(c[n+](c1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)n4cnc5c4ncnc5N)OP(=O)(O)O)O)O)O)C(=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 1DQA
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Color Legend
Unassigned regionsLigand / hetero atomse1dqaA1e1dqaA2e1dqaB1e1dqaB2e1dqaC1e1dqaC2e1dqaD1e1dqaD2
ECOD domains from experimental PDB structures interacting with ligand DB03461
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P04035 | DB03461 | NAP | 1dqa | e1dqaA1 | A:587-703 |
| P04035 | DB03461 | NAP | 1dqa | e1dqaA2 | A:462-586,A:704-870 |
| P04035 | DB03461 | NAP | 1dqa | e1dqaB1 | B:587-703 |
| P04035 | DB03461 | NAP | 1dqa | e1dqaB2 | B:462-586,B:704-866 |
| P04035 | DB03461 | NAP | 1dqa | e1dqaC1 | C:587-703 |
| P04035 | DB03461 | NAP | 1dqa | e1dqaC2 | C:468-586,C:704-871 |
| P04035 | DB03461 | NAP | 1dqa | e1dqaD1 | D:587-703 |
| P04035 | DB03461 | NAP | 1dqa | e1dqaD2 | D:477-586,D:704-871 |