Dabrafenib
P04049 — RAF proto-oncogene serine/threonine-protein kinase
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB08912
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| P04049 | DB08912 | P06 | nD3 | 206.1.1 | Protein kinase/SAICAR synthase/ATP-grasp | Protein kinase/SAICAR synthase/ATP-grasp | Protein kinase | PK_Tyr_Ser-Thr |
Show other predicted domains (11)
| PDB ID | Domain Name | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|
| 1C1Y | e1c1yB1 | 221.1.1 | beta-Grasp | Ubiquitin-related | Ubiquitin-like | Fer2 |
| 1FAQ | e1faqA1 | 376.1.2 | RING/U-box-like | RING/U-box-like | Cysteine-rich domain | C1_1 |
| 1FAR | e1farA1 | 376.1.2 | RING/U-box-like | RING/U-box-like | Cysteine-rich domain | C1_1 |
| 1GUA | e1guaB1 | 221.1.1 | beta-Grasp | Ubiquitin-related | Ubiquitin-like | Fer2 |
| 1RFA | e1rfaA1 | 221.1.1 | beta-Grasp | Ubiquitin-related | Ubiquitin-like | Fer2 |
| 3KUC | e3kucB1 | 221.1.1 | beta-Grasp | Ubiquitin-related | Ubiquitin-like | Fer2 |
| 3KUD | e3kudB1 | 221.1.1 | beta-Grasp | Ubiquitin-related | Ubiquitin-like | Fer2 |
| 3OMV | e3omvA1 | 206.1.1 | Protein kinase/SAICAR synthase/ATP-grasp | Protein kinase/SAICAR synthase/ATP-grasp | Protein kinase | Pkinase |
| e3omvB1 | 206.1.1 | Protein kinase/SAICAR synthase/ATP-grasp | Protein kinase/SAICAR synthase/ATP-grasp | Protein kinase | Pkinase | |
| 4G0N | e4g0nB1 | 221.1.1 | beta-Grasp | Ubiquitin-related | Ubiquitin-like | Fer2 |
| 4G3X | e4g3xB1 | 221.1.1 | beta-Grasp | Ubiquitin-related | Ubiquitin-like | Fer2 |
ECOD domains from experimental PDB structures interacting with ligand DB08912
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| No experimental ECOD data found | ||||||||||