DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
High affinity nerve growth factor receptor
Ligand Name
5-chloranyl-N2-[(1S)-1-(5-fluoranylpyridin-2-yl)ethyl]-N4-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
LBVKEEFIPBQIMD-JTQLQIEISA-N
SMILES
CC(C)Oc1cc([nH]n1)Nc2c(cnc(n2)NC(C)c3ccc(cn3)F)Cl
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 4AOJ
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse4aojA1e4aojB1e4aojC1
ECOD domains from experimental PDB structures interacting with ligand V4Z
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P04629n/aV4Z4aoje4aojA1A:500-789
P04629n/aV4Z4aoje4aojB1B:500-669,B:689-791
P04629n/aV4Z4aoje4aojC1C:500-789