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[6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl]methyl dihydrogen phosphate

P06213 — Insulin receptor

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB12010

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
P06213DB120102RCnD2389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainFurin-like
P06213DB120102RCnD611.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likefn3, PK_Tyr_Ser-Thr, Insulin_TMD
Show other predicted domains (78)
PDB IDDomain NameECOD IDX GroupH GroupT GroupF Group
1GAGe1gagA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
1I44e1i44A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
1IR3e1ir3A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
1IRKe1irkA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
1P14e1p14A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
1RQQe1rqqB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e1rqqA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
2AUHe2auhA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
2B4Se2b4sD1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e2b4sB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
2HR7e2hr7A2207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e2hr7A3207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e2hr7B1207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e2hr7B3207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e2hr7A1389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e2hr7B2389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
2MFRe2mfrA13569.2.1Epidermal growth factor receptor transmembrane-juxtamembrane segment-likeInsulin receptor transmembrane segmentInsulin receptor transmembrane segmentInsulin_TMD
2Z8Ce2z8cA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3BU3e3bu3A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3BU5e3bu5A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3BU6e3bu6A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3EKKe3ekkA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3EKNe3eknA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3ETAe3etaA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3etaB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3W11e3w11E3207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3w11E4389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
3W12e3w12E3207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3w12E4389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
3W13e3w13E3207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3w13E4389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
4IBMe4ibmA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4ibmB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4OGAe4ogaE2207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e4ogaE1389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
4XLVe4xlvA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4XSSe4xssE2207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e4xssE1389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
4XSTe4xstE1207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e4xstE2389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
4ZXBe4zxbE111.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likeCadherin
e4zxbE211.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likeCadherin
e4zxbE311.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likeCadherin
e4zxbE5207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e4zxbE7207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e4zxbE6389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
5E1Se5e1sA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
5HHWe5hhwA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
5J3He5j3hE1207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e5j3hE2389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
5KQVe5kqvE311.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likeCadherin
e5kqvF111.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likeCadherin
e5kqvE1207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e5kqvE2207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e5kqvF3207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e5kqvF4207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e5kqvE4389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e5kqvF2389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
6HN4e6hn4E111.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likeCadherin
e6hn4E211.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likeCadherin
e6hn4F311.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likeCadherin
e6hn4F411.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likeCadherin
e6hn4F2207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e6hn4F1389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
6HN5e6hn5E311.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likeCadherin
e6hn5F211.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likeCadherin
e6hn5E2207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e6hn5E4207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e6hn5F1207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e6hn5E1389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
6PXWe6pxwA411.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likeCadherin
e6pxwB311.1.1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedImmunoglobulin/Fibronectin type III/E set domains/PapD-likeCadherin
e6pxwA2207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e6pxwA3207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e6pxwB1207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e6pxwB2207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e6pxwA1389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e6pxwB4389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP

ECOD domains from experimental PDB structures interacting with ligand DB12010

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
No experimental ECOD data found