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3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide

P06239 — Tyrosine-protein kinase Lck

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB08901

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
P06239DB089010LInD3206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePK_Tyr_Ser-Thr
Show other predicted domains (70)
PDB IDDomain NameECOD IDX GroupH GroupT GroupF Group
1BHFe1bhfA1214.1.1SH2SH2SH2SH2
1BHHe1bhhA1214.1.1SH2SH2SH2SH2
e1bhhB1214.1.1SH2SH2SH2SH2
1CWDe1cwdL1214.1.1SH2SH2SH2SH2
1CWEe1cweA1214.1.1SH2SH2SH2SH2
e1cweC1214.1.1SH2SH2SH2SH2
1FBZe1fbzA1214.1.1SH2SH2SH2SH2
e1fbzB1214.1.1SH2SH2SH2SH2
1H92e1h92A14.1.1SH3SH3SH3SH3_1
1IJRe1ijrA1214.1.1SH2SH2SH2SH2
1KIKe1kikA14.1.1SH3SH3SH3SH3_1
1LCJe1lcjA1214.1.1SH2SH2SH2SH2
1LCKe1lckA2214.1.1SH2SH2SH2SH2
e1lckA14.1.1SH3SH3SH3SH3_1
1LKKe1lkkA1214.1.1SH2SH2SH2SH2
1LKLe1lklA1214.1.1SH2SH2SH2SH2
1QPCe1qpcA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
1QPDe1qpdA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
1QPEe1qpeA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
1QPJe1qpjA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
1X27e1x27A2214.1.1SH2SH2SH2SH2
e1x27D2214.1.1SH2SH2SH2SH2
e1x27B2214.1.1SH2SH2SH2SH2
e1x27F2214.1.1SH2SH2SH2SH2
e1x27E2214.1.1SH2SH2SH2SH2
e1x27C2214.1.1SH2SH2SH2SH2
e1x27B14.1.1SH3SH3SH3SH3_1
e1x27E14.1.1SH3SH3SH3SH3_1
e1x27D14.1.1SH3SH3SH3SH3_1
e1x27A14.1.1SH3SH3SH3SH3_1
e1x27F14.1.1SH3SH3SH3SH3_1
e1x27C14.1.1SH3SH3SH3SH3_1
2IIMe2iimA14.1.1SH3SH3SH3SH3_1
2OF2e2of2A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
2OF4e2of4A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
2OFUe2ofuA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
2OFVe2ofvB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e2ofvA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
2OG8e2og8B1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e2og8A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
2PL0e2pl0A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
2ZM1e2zm1A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
2ZM4e2zm4A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
2ZYBe2zybA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3AC1e3ac1A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3AC2e3ac2A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3AC3e3ac3A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3AC4e3ac4A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3AC5e3ac5A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3AC8e3ac8A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3ACJe3acjA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3ACKe3ackA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3AD4e3ad4A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3AD5e3ad5A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3AD6e3ad6A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3B2We3b2wA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3BYMe3bymA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3BYOe3byoA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3BYSe3bysA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3BYUe3byuA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3KMMe3kmmA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3KXZe3kxzA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3LCKe3lckA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3MPMe3mpmA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4C3Fe4c3fA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4D8Ke4d8kA3214.1.1SH2SH2SH2SH2
e4d8kA44.1.1SH3SH3SH3SH3_1
5MTMe5mtmA1214.1.1SH2SH2SH2SH2
5MTNe5mtnA1214.1.1SH2SH2SH2SH2
6PDJe6pdjA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase

ECOD domains from experimental PDB structures interacting with ligand DB08901

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
No experimental ECOD data found