Attributes
UniProt ID
Protein Name
DNA topoisomerase 1
Ligand Name
THYMIDINE-5'-PHOSPHATE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
GYOZYWVXFNDGLU-XLPZGREQSA-N
SMILES
CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)(O)O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 1CY1
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Color Legend
Unassigned regionsLigand / hetero atomse1cy1A1e1cy1A2e1cy1A3e1cy1A4
ECOD domains from experimental PDB structures interacting with ligand DB01643
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P06612 | DB01643 | TMP | 1cy1 | e1cy1A2 | A:156-213,A:472-591 |
| P06612 | DB01643 | TMP | 1cy1 | e1cy1A3 | A:280-402 |
| P06612 | DB01643 | TMP | 1cy2 | e1cy2A2 | A:157-214,A:461-594 |
| P06612 | DB01643 | TMP | 1cy2 | e1cy2A3 | A:281-395 |
| P06612 | DB01643 | TMP | 1cy4 | e1cy4A1 | A:2-39,A:63-156 |
| P06612 | DB01643 | TMP | 1cy4 | e1cy4A2 | A:157-214,A:461-596 |
| P06612 | DB01643 | TMP | 1cy4 | e1cy4A3 | A:281-395 |
| P06612 | DB01643 | TMP | 1cy7 | e1cy7A2 | A:157-214,A:461-596 |
| P06612 | DB01643 | TMP | 1cy7 | e1cy7A3 | A:281-395 |
| P06612 | DB01643 | TMP | 1cy8 | e1cy8A2 | A:157-214,A:461-595 |
| P06612 | DB01643 | TMP | 1cy8 | e1cy8A3 | A:281-395 |
| P06612 | DB01643 | TMP | 1mw8 | e1mw8X1 | X:2-39,X:63-156 |
| P06612 | DB01643 | TMP | 1mw8 | e1mw8X2 | X:157-214,X:461-592 |
| P06612 | DB01643 | TMP | 1mw8 | e1mw8X3 | X:281-395 |