MONO-{4-[(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-AMINO]-2-HYDROXY-3-MERCAPTO-PENT-3-ENYL-PHOSPHONO} ESTER

P06672 — Pyruvate decarboxylase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DPX

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DPX

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P06672	n/a	1zpd	DPX	A	600	e1zpdA2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P06672	n/a	1zpd	DPX	A	600	e1zpdA3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P06672	n/a	1zpd	DPX	A	600	e1zpdB2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P06672	n/a	1zpd	DPX	B	600	e1zpdA2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P06672	n/a	1zpd	DPX	B	600	e1zpdB3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P06672	n/a	1zpd	DPX	E	600	e1zpdE3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P06672	n/a	1zpd	DPX	E	600	e1zpdF2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P06672	n/a	1zpd	DPX	F	600	e1zpdE2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P06672	n/a	1zpd	DPX	F	600	e1zpdE3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P06672	n/a	1zpd	DPX	F	600	e1zpdF3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C