3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-CARBOXY-1-HYDROXYETHYL)-5-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM

P06672 — Pyruvate decarboxylase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand TDL

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand TDL

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P06672	n/a	3oe1	TDL	A	611	e3oe1A1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
P06672	n/a	3oe1	TDL	A	611	e3oe1A2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P06672	n/a	3oe1	TDL	A	611	e3oe1A3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P06672	n/a	3oe1	TDL	A	611	e3oe1B2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P06672	n/a	3oe1	TDL	B	611	e3oe1A2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P06672	n/a	3oe1	TDL	B	611	e3oe1B1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
P06672	n/a	3oe1	TDL	B	611	e3oe1B3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P06672	n/a	3oe1	TDL	C	611	e3oe1C1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
P06672	n/a	3oe1	TDL	C	611	e3oe1C3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P06672	n/a	3oe1	TDL	C	611	e3oe1D2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P06672	n/a	3oe1	TDL	D	611	e3oe1C2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P06672	n/a	3oe1	TDL	D	611	e3oe1D1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
P06672	n/a	3oe1	TDL	D	611	e3oe1D3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C