DrugDomain logoDrugDomain

~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (~{E})-but-2-enethioate

P07149 Fatty acid synthase subunit beta dehydratase ; Enoyl- reductase ; acetyltransferase ; malonyltransferase ; S-acyl fatty acid synthase thioesterase ]

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand A3Z

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand A3Z

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P07149n/a8ps2A3ZB1901e8ps2G11Alpha-beta plaitsProbable ACP-binding domain of malonyl-CoA ACP transacylaseProbable ACP-binding domain of malonyl-CoA ACP transacylaseSAT
P07149n/a8ps2A3ZB1901e8ps2G3Inserted helical domain in fatty acid synthase subunit betaInserted helical domain in fatty acid synthase subunit betaInserted helical domain in fatty acid synthase subunit betaFas1-AflB-like_hel
P07149n/a8ps2A3ZB1901e8ps2G7TIM beta/alpha-barrelTIM barrelsTIM barrelsFas1-AflB-like_hel