Attributes
UniProt ID
Protein Name
Acetolactate synthase catalytic subunit, mitochondrial
Ligand Name
2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
SYJGKVOENHZYMQ-UHFFFAOYSA-N
SMILES
COc1cnc(n2c1nc(n2)NS(=O)(=O)c3c(cccc3OCC(F)F)C(F)(F)F)OC
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 5WKC
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Color Legend
Unassigned regionsLigand / hetero atomse5wkcA1e5wkcA2e5wkcA3e5wkcB1e5wkcB2e5wkcB3e5wkcD1e5wkcD2e5wkcD3e5wkcE1e5wkcE2e5wkcE3
ECOD domains from experimental PDB structures interacting with ligand PXD
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P07342 | n/a | PXD | 5wkc | e5wkcA1 | A:290-460 |
| P07342 | n/a | PXD | 5wkc | e5wkcA2 | A:85-289 |
| P07342 | n/a | PXD | 5wkc | e5wkcA3 | A:461-687 |
| P07342 | n/a | PXD | 5wkc | e5wkcB1 | B:83-289 |
| P07342 | n/a | PXD | 5wkc | e5wkcB2 | B:290-460 |
| P07342 | n/a | PXD | 5wkc | e5wkcB3 | B:461-687 |
| P07342 | n/a | PXD | 5wkc | e5wkcD1 | D:84-289 |
| P07342 | n/a | PXD | 5wkc | e5wkcD2 | D:461-687 |
| P07342 | n/a | PXD | 5wkc | e5wkcD3 | D:290-460 |
| P07342 | n/a | PXD | 5wkc | e5wkcE1 | E:461-687 |
| P07342 | n/a | PXD | 5wkc | e5wkcE2 | E:84-289 |
| P07342 | n/a | PXD | 5wkc | e5wkcE3 | E:290-460 |