Zinc

P07357 — Complement component C8 alpha chain

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB01593

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P07357	DB01593	n/a	nD1	922.1.1	TSP-1 type 1 repeat	TSP-1 type 1 repeat	TSP-1 type 1 repeat	n/a
P07357	DB01593	n/a	nD2	389.3.1	EGF-like	LDL receptor-like module	LDL receptor-like module	Ldl_recept_a
P07357	DB01593	n/a	nD3	5089.1.1	Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains	Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains	Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains	MACPF
P07357	DB01593	n/a	nD4	389.1.1	EGF-like	EGF-related	EGF/Laminin	C8A_B_C6_EGF-like

Show other predicted domains (7)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
2QQH	e2qqhA1	5089.1.1	Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains	Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains	Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains	Thiol_cytolysin
2RD7	e2rd7A1	5089.1.1	Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains	Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains	Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains	Thiol_cytolysin
3OJY	e3ojyA4	389.1.1	EGF-like	EGF-related	EGF/Laminin	EGF
	e3ojyA2	389.3.1	EGF-like	LDL receptor-like module	LDL receptor-like module	Ldl_recept_a
	e3ojyA3	5089.1.1	Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains	Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains	Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains	Thiol_cytolysin
	e3ojyA1	922.1.1	TSP-1 type 1 repeat	TSP-1 type 1 repeat	TSP-1 type 1 repeat	TSP_1
	e3ojyA5	922.1.1	TSP-1 type 1 repeat	TSP-1 type 1 repeat	TSP-1 type 1 repeat	TSP_1

ECOD domains from experimental PDB structures interacting with ligand DB01593

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found