Attributes
UniProt ID
Protein Name
Bifunctional glutamate/proline--tRNA ligase
Ligand Name
4-[(3S)-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(5-methoxypyridin-3-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
RXELMDABJFGOHE-MUUNZHRXSA-N
SMILES
Cc1cc(cc(n1)C(=O)NCc2cc(cc(c2)F)c3cc(cnc3)OC)N4CCC(C4=O)(C#N)C5CC5
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 7F99
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Color Legend
Unassigned regionsLigand / hetero atomse7f99A1e7f99A2e7f99A3e7f99B1e7f99B2e7f99B3
ECOD domains from experimental PDB structures interacting with ligand 1UI
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P07814 | n/a | 1UI | 7f99 | e7f99A1 | A:1016-1291 |
| P07814 | n/a | 1UI | 7f99 | e7f99A3 | A:1420-1512 |
| P07814 | n/a | 1UI | 7f99 | e7f99B3 | B:1015-1291 |
| P07814 | n/a | 1UI | 7f9c | e7f9cA2 | A:1016-1291 |
| P07814 | n/a | 1UI | 7f9c | e7f9cA3 | A:1420-1512 |
| P07814 | n/a | 1UI | 7f9c | e7f9cB1 | B:1015-1291 |
| P07814 | n/a | 1UI | 7f9c | e7f9cB3 | B:1420-1512 |
| P07814 | n/a | 1UI | 7f9d | e7f9dA1 | A:1015-1291 |
| P07814 | n/a | 1UI | 7f9d | e7f9dA2 | A:1420-1512 |
| P07814 | n/a | 1UI | 7f9d | e7f9dB1 | B:1420-1512 |
| P07814 | n/a | 1UI | 7f9d | e7f9dB3 | B:1015-1291 |