Attributes
UniProt ID
Protein Name
Insulin-like growth factor 1 receptor
Ligand Name
4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
QEMHSTOIAUCOQF-UHFFFAOYSA-N
SMILES
Cn1ccnc1Sc2ccc(cc2Cl)Nc3c4cc(c(cc4ncc3C#N)OCCCN(C)CCO)OC
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 3F5P
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Color Legend
Unassigned regionsLigand / hetero atomse3f5pA1e3f5pB1e3f5pC1e3f5pD1e3f5pE1e3f5pF1e3f5pG1e3f5pH1e3f5pI1e3f5pJ1e3f5pK1e3f5pL1e3f5pM1e3f5pR1e3f5pS1e3f5pT1
ECOD domains from experimental PDB structures interacting with ligand 741
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P08069 | n/a | 741 | 3f5p | e3f5pA1 | A:980-1286 |
| P08069 | n/a | 741 | 3f5p | e3f5pB1 | B:980-1286 |
| P08069 | n/a | 741 | 3f5p | e3f5pC1 | C:980-1286 |
| P08069 | n/a | 741 | 3f5p | e3f5pD1 | D:980-1286 |
| P08069 | n/a | 741 | 3f5p | e3f5pE1 | E:980-1285 |
| P08069 | n/a | 741 | 3f5p | e3f5pF1 | F:980-1285 |
| P08069 | n/a | 741 | 3f5p | e3f5pG1 | G:980-1285 |
| P08069 | n/a | 741 | 3f5p | e3f5pH1 | H:980-1286 |
| P08069 | n/a | 741 | 3f5p | e3f5pI1 | I:980-1285 |
| P08069 | n/a | 741 | 3f5p | e3f5pJ1 | J:980-1285 |
| P08069 | n/a | 741 | 3f5p | e3f5pK1 | K:980-1285 |
| P08069 | n/a | 741 | 3f5p | e3f5pL1 | L:980-1285 |
| P08069 | n/a | 741 | 3f5p | e3f5pM1 | M:980-1285 |
| P08069 | n/a | 741 | 3f5p | e3f5pR1 | R:980-1285 |
| P08069 | n/a | 741 | 3f5p | e3f5pS1 | S:980-1286 |
| P08069 | n/a | 741 | 3f5p | e3f5pT1 | T:980-1286 |