Attributes
UniProt ID
Protein Name
Insulin-like growth factor 1 receptor
Ligand Name
3-[8-azanyl-1-(4-ethoxy-8-fluoranyl-2-phenyl-quinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutan-1-ol
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
TVXAIWDTRFFVCZ-OOTKOPMESA-N
SMILES
CCOc1cc(nc2c1ccc(c2F)c3c4c(nccn4c(n3)C5CC(C5)(C)O)N)c6ccccc6
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 8PYI
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Color Legend
Unassigned regionsLigand / hetero atomse8pyiAAA1e8pyiBBB1e8pyiCCC1e8pyiDDD1e8pyiEEE1e8pyiFFF1e8pyiGGG1e8pyiHHH1
ECOD domains from experimental PDB structures interacting with ligand IER
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P08069 | n/a | IER | 8pyi | e8pyiAAA1 | AAA:986-1286 |
| P08069 | n/a | IER | 8pyi | e8pyiBBB1 | BBB:986-1285 |
| P08069 | n/a | IER | 8pyi | e8pyiCCC1 | CCC:987-1285 |
| P08069 | n/a | IER | 8pyi | e8pyiDDD1 | DDD:987-1285 |
| P08069 | n/a | IER | 8pyi | e8pyiEEE1 | EEE:987-1285 |
| P08069 | n/a | IER | 8pyi | e8pyiFFF1 | FFF:987-1285 |
| P08069 | n/a | IER | 8pyi | e8pyiGGG1 | GGG:987-1285 |
| P08069 | n/a | IER | 8pyi | e8pyiHHH1 | HHH:987-1285 |