Attributes
UniProt ID
Protein Name
Isocitrate dehydrogenase -dependent isocitric dehydrogenase) -specific ICDH
Ligand Name
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XJLXINKUBYWONI-NNYOXOHSSA-N
SMILES
c1cc(c[n+](c1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)n4cnc5c4ncnc5N)OP(=O)(O)O)O)O)O)C(=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 1AI2
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Color Legend
Unassigned regionsLigand / hetero atomse1ai2A1e1ai2A2
ECOD domains from experimental PDB structures interacting with ligand DB03461
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P08200 | DB03461 | NAP | 1ai2 | e1ai2A1 | A:124-318 |
| P08200 | DB03461 | NAP | 1ai2 | e1ai2A2 | A:3-123,A:317-416 |
| P08200 | DB03461 | NAP | 1bl5 | e1bl5A2 | A:3-123,A:317-416 |
| P08200 | DB03461 | NAP | 1hj6 | e1hj6A2 | A:3-123,A:317-416 |
| P08200 | DB03461 | NAP | 1ide | e1ideA1 | A:124-318 |
| P08200 | DB03461 | NAP | 1ide | e1ideA2 | A:3-123,A:317-416 |
| P08200 | DB03461 | NAP | 4aj3 | e4aj3A1 | A:124-318 |
| P08200 | DB03461 | NAP | 4aj3 | e4aj3A2 | A:1-123,A:317-416 |
| P08200 | DB03461 | NAP | 4ajr | e4ajrA1 | A:124-318 |
| P08200 | DB03461 | NAP | 4ajr | e4ajrA2 | A:2-123,A:317-416 |
| P08200 | DB03461 | NAP | 9icd | e9icdA2 | A:3-123,A:317-416 |