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4-[(4R)-7-methyl-2,5-bis(oxidanylidene)-1-[3-(trifluoromethyl)phenyl]-3,4,6,8-tetrahydropyrimido[4,5-d]pyridazin-4-yl]benzenecarbonitrile

P08246 — Neutrophil elastase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand IUL

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand IUL

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P08246n/a5a8zIULA1001e5a8zA1cradle loop barrelRIFT-relatedFMN-binding split barrel 2Trypsin