7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one

P08253 — 72 kDa type IV collagenase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB04866

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P08253	DB04866	HFG	nD1	144.1.1	PGBD-like	PGBD-like	PGBD-like	PG_binding_1
P08253	DB04866	HFG	nD2	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
P08253	DB04866	HFG	nD3	2498.1.1	Zincin-like	Metalloproteases ("zincins") catalytic domain	Metalloproteases ("zincins") catalytic domain	Peptidase_M10
P08253	DB04866	HFG	nD4	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
P08253	DB04866	HFG	nD5	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
P08253	DB04866	HFG	nD6	5.1.1	beta-propeller-like	beta-propeller	4-bladed	Hemopexin

Show other predicted domains (46)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
1CK7	e1ck7A2	144.1.1	PGBD-like	PGBD-like	PGBD-like	PG_binding_1
	e1ck7A6	2498.1.1	Zincin-like	Metalloproteases ("zincins") catalytic domain	Metalloproteases ("zincins") catalytic domain	Peptidase_M10
	e1ck7A3	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1ck7A4	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1ck7A5	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1ck7A1	5.1.1	beta-propeller-like	beta-propeller	4-bladed	Hemopexin
1CXW	e1cxwA1	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
1EAK	e1eakB1	144.1.1	PGBD-like	PGBD-like	PGBD-like	PG_binding_1
	e1eakD1	144.1.1	PGBD-like	PGBD-like	PGBD-like	PG_binding_1
	e1eakC1	144.1.1	PGBD-like	PGBD-like	PGBD-like	PG_binding_1
	e1eakA1	144.1.1	PGBD-like	PGBD-like	PGBD-like	PG_binding_1
	e1eakA5	2498.1.1	Zincin-like	Metalloproteases ("zincins") catalytic domain	Metalloproteases ("zincins") catalytic domain	Peptidase_M10
	e1eakB5	2498.1.1	Zincin-like	Metalloproteases ("zincins") catalytic domain	Metalloproteases ("zincins") catalytic domain	Peptidase_M10
	e1eakC5	2498.1.1	Zincin-like	Metalloproteases ("zincins") catalytic domain	Metalloproteases ("zincins") catalytic domain	Peptidase_M10
	e1eakD5	2498.1.1	Zincin-like	Metalloproteases ("zincins") catalytic domain	Metalloproteases ("zincins") catalytic domain	Peptidase_M10
	e1eakD2	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1eakB2	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1eakA2	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1eakD3	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1eakC2	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1eakC3	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1eakD4	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1eakC4	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1eakA3	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1eakB3	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1eakA4	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1eakB4	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
1GEN	e1genA1	5.1.1	beta-propeller-like	beta-propeller	4-bladed	Hemopexin
1GXD	e1gxdB2	144.1.1	PGBD-like	PGBD-like	PGBD-like	PG_binding_1
	e1gxdA4	144.1.1	PGBD-like	PGBD-like	PGBD-like	PG_binding_1
	e1gxdB6	2498.1.1	Zincin-like	Metalloproteases ("zincins") catalytic domain	Metalloproteases ("zincins") catalytic domain	Peptidase_M10
	e1gxdA3	2498.1.1	Zincin-like	Metalloproteases ("zincins") catalytic domain	Metalloproteases ("zincins") catalytic domain	Peptidase_M10
	e1gxdB3	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1gxdB4	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1gxdB5	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1gxdA1	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1gxdA2	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1gxdA6	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
	e1gxdB1	5.1.1	beta-propeller-like	beta-propeller	4-bladed	Hemopexin
	e1gxdA5	5.1.1	beta-propeller-like	beta-propeller	4-bladed	Hemopexin
1HOV	e1hovA1	2498.1.1	Zincin-like	Metalloproteases ("zincins") catalytic domain	Metalloproteases ("zincins") catalytic domain	Peptidase_M10
1J7M	e1j7mA1	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
1KS0	e1ks0A1	380.1.1	Kringle-like	Kringle-like	Kringle-like	fn2
1QIB	e1qibA1	2498.1.1	Zincin-like	Metalloproteases ("zincins") catalytic domain	Metalloproteases ("zincins") catalytic domain	Peptidase_M10
1RTG	e1rtgA1	5.1.1	beta-propeller-like	beta-propeller	4-bladed	Hemopexin
3AYU	e3ayuA1	2498.1.1	Zincin-like	Metalloproteases ("zincins") catalytic domain	Metalloproteases ("zincins") catalytic domain	Peptidase_M10

ECOD domains from experimental PDB structures interacting with ligand DB04866

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found