DrugDomain logoDrugDomain

Attributes

UniProt ID
P08684
Protein Name
Cytochrome P450 3A4
Ligand Name
PROTOPORPHYRIN IX CONTAINING FE
DrugBank ID
DB18267
PDB Ligand Accession
HEM
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KABFMIBPWCXCRK-RGGAHWMASA-L
SMILES
Cc1c2n3c(c1CCC(=O)O)C=C4C(=C(C5=[N]4[Fe]36[N]7=C(C=C8N6C(=C5)C(=C8C)C=C)C(=C(C7=C2)C)C=C)C)CCC(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Mol*
Structure: 1TQN
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Color Legend
Unassigned regionsLigand / hetero atomse1tqnA1
ECOD domains from experimental PDB structures interacting with ligand DB18267
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P08684DB18267HEM1tqne1tqnA1A:28-499
P08684DB18267HEM1w0ee1w0eA1A:28-497
P08684DB18267HEM1w0fe1w0fA1A:28-498
P08684DB18267HEM1w0ge1w0gA1A:28-498
P08684DB18267HEM2j0de2j0dA1A:30-496
P08684DB18267HEM2j0de2j0dB1B:30-496
P08684DB18267HEM2v0me2v0mA1A:30-498
P08684DB18267HEM2v0me2v0mB1B:30-496
P08684DB18267HEM2v0me2v0mC1C:30-496
P08684DB18267HEM2v0me2v0mD1D:30-496
P08684DB18267HEM3nxue3nxuA1A:29-496
P08684DB18267HEM3nxue3nxuB1B:29-496
P08684DB18267HEM3tjse3tjsA1A:24-496
P08684DB18267HEM3ua1e3ua1A1A:28-496
P08684DB18267HEM4d6ze4d6zA1A:29-497
P08684DB18267HEM4d75e4d75A1A:28-496
P08684DB18267HEM4d78e4d78A1A:27-475
P08684DB18267HEM4d7de4d7dA1A:29-497
P08684DB18267HEM4i3qe4i3qA1A:28-497
P08684DB18267HEM4i4ge4i4gA1A:22-479
P08684DB18267HEM4i4he4i4hA1A:21-477
P08684DB18267HEM4k9te4k9tA1A:29-497
P08684DB18267HEM4k9ue4k9uA1A:27-496
P08684DB18267HEM4k9ve4k9vA1A:28-496
P08684DB18267HEM4k9we4k9wA1A:29-496
P08684DB18267HEM4k9we4k9wB1B:29-496
P08684DB18267HEM4k9we4k9wC1C:29-496
P08684DB18267HEM4k9we4k9wD1D:29-496
P08684DB18267HEM4k9xe4k9xA1A:29-496
P08684DB18267HEM4ny4e4ny4A1A:28-498
P08684DB18267HEM5a1pe5a1pA1A:26-475
P08684DB18267HEM5a1re5a1rA1A:26-475
P08684DB18267HEM5g5je5g5jA1A:28-497
P08684DB18267HEM5te8e5te8A1A:2-497
P08684DB18267HEM5te8e5te8B1B:2-497
P08684DB18267HEM5te8e5te8C1C:2-496
P08684DB18267HEM5vc0e5vc0A1A:28-496
P08684DB18267HEM5vcce5vccA1A:29-496
P08684DB18267HEM5vcde5vcdA1A:26-496
P08684DB18267HEM5vcee5vceA1A:26-496
P08684DB18267HEM5vcge5vcgA1A:28-497
P08684DB18267HEM6bcze6bczA1A:27-496
P08684DB18267HEM6bd5e6bd5A1A:29-496
P08684DB18267HEM6bd6e6bd6A1A:28-496
P08684DB18267HEM6bd7e6bd7A1A:28-497
P08684DB18267HEM6bd8e6bd8A1A:29-496
P08684DB18267HEM6bdhe6bdhA1A:28-496
P08684DB18267HEM6bdie6bdiA1A:27-497
P08684DB18267HEM6bdke6bdkA1A:27-497
P08684DB18267HEM6bdme6bdmA1A:28-496
P08684DB18267HEM6da2e6da2A1A:28-496
P08684DB18267HEM6da3e6da3A1A:27-496
P08684DB18267HEM6da5e6da5A1A:27-496
P08684DB18267HEM6da8e6da8A1A:27-496
P08684DB18267HEM6daae6daaA1A:27-496
P08684DB18267HEM6dabe6dabA1A:29-496
P08684DB18267HEM6dace6dacA1A:27-496
P08684DB18267HEM6dage6dagA1A:27-496
P08684DB18267HEM6daje6dajA1A:28-496
P08684DB18267HEM6dale6dalA1A:27-496
P08684DB18267HEM6ma6e6ma6A1A:26-497
P08684DB18267HEM6ma7e6ma7A1A:26-497
P08684DB18267HEM6ma8e6ma8A1A:26-497
P08684DB18267HEM6oo9e6oo9A1A:26-496
P08684DB18267HEM6ooae6ooaA1A:28-496
P08684DB18267HEM6oobe6oobA1A:26-496
P08684DB18267HEM6unee6uneA1A:29-496
P08684DB18267HEM6unge6ungA1A:28-496
P08684DB18267HEM6unhe6unhA1A:27-497
P08684DB18267HEM6unie6uniA1A:27-197,A:218-496
P08684DB18267HEM6unje6unjA1A:29-496
P08684DB18267HEM6unje6unjB1B:29-496
P08684DB18267HEM6unke6unkA1A:27-496
P08684DB18267HEM6unle6unlA1A:27-197,A:218-496
P08684DB18267HEM6unme6unmA1A:28-496
P08684DB18267HEM6unme6unmB1B:29-495
P08684DB18267HEM7ks8e7ks8A1A:28-497
P08684DB18267HEM7ksae7ksaA1A:28-496
P08684DB18267HEM7kvhe7kvhA1A:29-496
P08684DB18267HEM7kvhe7kvhB1B:29-496
P08684DB18267HEM7kvie7kviA1A:28-496
P08684DB18267HEM7kvje7kvjA1A:28-194,A:218-496
P08684DB18267HEM7kvke7kvkA1A:27-496
P08684DB18267HEM7kvke7kvkB1B:29-496
P08684DB18267HEM7kvme7kvmA1A:28-496
P08684DB18267HEM7kvne7kvnA1A:29-496
P08684DB18267HEM7kvne7kvnB1B:29-496
P08684DB18267HEM7kvoe7kvoA1A:29-496
P08684DB18267HEM7kvoe7kvoB1B:29-496
P08684DB18267HEM7kvpe7kvpA1A:29-497
P08684DB18267HEM7kvqe7kvqA1A:29-496
P08684DB18267HEM7kvqe7kvqB1B:29-496
P08684DB18267HEM7kvse7kvsA1A:28-496
P08684DB18267HEM7kvse7kvsB1B:29-495
P08684DB18267HEM7lxle7lxlA1A:28-496
P08684DB18267HEM7uaye7uayA1A:29-496
P08684DB18267HEM7uaze7uazA1A:28-496
P08684DB18267HEM7uf9e7uf9A1A:27-496
P08684DB18267HEM7ufae7ufaA1A:28-497
P08684DB18267HEM7ufbe7ufbA1A:27-497
P08684DB18267HEM7ufce7ufcA1A:27-496
P08684DB18267HEM7ufde7ufdA1A:27-496
P08684DB18267HEM7ufee7ufeA1A:26-496
P08684DB18267HEM7ufee7ufeB1B:29-496
P08684DB18267HEM7uffe7uffA1A:29-496
P08684DB18267HEM7uffe7uffB1B:29-496
P08684DB18267HEM8dyce8dycA1A:26-497
P08684DB18267HEM8ewde8ewdA1A:29-496
P08684DB18267HEM8ewee8eweA1A:26-496
P08684DB18267HEM8ewle8ewlA1A:27-496
P08684DB18267HEM8ewme8ewmA1A:27-497
P08684DB18267HEM8ewne8ewnA1A:28-496
P08684DB18267HEM8ewpe8ewpA1A:27-496
P08684DB18267HEM8ewqe8ewqA1A:26-496
P08684DB18267HEM8ewre8ewrA1A:29-496
P08684DB18267HEM8ewse8ewsA1A:27-497
P08684DB18267HEM8exbe8exbA1A:29-496
P08684DB18267HEM8so1e8so1A1A:26-496
P08684DB18267HEM8so2e8so2A1A:26-497
P08684DB18267HEM8spde8spdA1A:28-496