~{N}-[(1~{R})-1-(4-imidazol-1-ylphenyl)ethyl]-3-(4-oxidanylidene-1~{H}-quinazolin-2-yl)propanamide
P09874 — Poly polymerase 1 ADP-ribosyltransferase 1) polymerase 1, processed C-terminus ; Poly polymerase 1, processed N-terminus ]
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand EZ2
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand EZ2
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P09874 | n/a | 6ghk | EZ2 | A | 1101 | e6ghkA1 | Domain of poly(ADP-ribose) polymerase | Domain of poly(ADP-ribose) polymerase | Domain of poly(ADP-ribose) polymerase | PARP_reg |
| P09874 | n/a | 6ghk | EZ2 | A | 1101 | e6ghkA2 | ADP-ribosylation | ADP-ribosylation | ADP-ribosylation | PARP |
| P09874 | n/a | 6ghk | EZ2 | B | 1101 | e6ghkB1 | ADP-ribosylation | ADP-ribosylation | ADP-ribosylation | PARP |
| P09874 | n/a | 6ghk | EZ2 | B | 1101 | e6ghkB2 | Domain of poly(ADP-ribose) polymerase | Domain of poly(ADP-ribose) polymerase | Domain of poly(ADP-ribose) polymerase | PARP_reg |