Attributes
UniProt ID
Protein Name
Leukotriene A-4 hydrolase hydrolase
Ligand Name
1-{4-oxo-4-[(2S)-pyrrolidin-2-yl]butanoyl}-L-proline
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
FCVBOVVXXBUFFZ-UWVGGRQHSA-N
SMILES
C1CC(NC1)C(=O)CCC(=O)N2CCCC2C(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 4MKT
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Color Legend
Unassigned regionsLigand / hetero atomse4mktA1e4mktA2e4mktA3
ECOD domains from experimental PDB structures interacting with ligand 28T
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P09960 | n/a | 28T | 4mkt | e4mktA1 | A:3-208 |
| P09960 | n/a | 28T | 4mkt | e4mktA2 | A:461-610 |
| P09960 | n/a | 28T | 4mkt | e4mktA3 | A:209-460 |
| P09960 | n/a | 28T | 4ms6 | e4ms6A1 | A:3-208 |
| P09960 | n/a | 28T | 4ms6 | e4ms6A2 | A:461-610 |
| P09960 | n/a | 28T | 4ms6 | e4ms6A3 | A:209-460 |
| P09960 | n/a | 28T | 7llq | e7llqA1 | A:3-208 |
| P09960 | n/a | 28T | 7llq | e7llqA2 | A:461-610 |
| P09960 | n/a | 28T | 7llq | e7llqA3 | A:209-460 |
| P09960 | n/a | 28T | 7llq | e7llqB1 | B:3-208 |
| P09960 | n/a | 28T | 7llq | e7llqB2 | B:209-460 |
| P09960 | n/a | 28T | 7llq | e7llqB3 | B:461-610 |
| P09960 | n/a | 28T | 7llq | e7llqC1 | C:209-460 |
| P09960 | n/a | 28T | 7llq | e7llqC2 | C:461-610 |
| P09960 | n/a | 28T | 7llq | e7llqC3 | C:3-208 |