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Attributes

UniProt ID
P0A017
Protein Name
Dihydrofolate reductase
Ligand Name
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
DB02338
PDB Ligand Accession
NDP
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ACFIXJIJDZMPPO-NNYOXOHSSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=CCC(=C5)C(=O)N)O)O)O)OP(=O)(O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Mol*
Structure: 2W9G
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Color Legend
Unassigned regionsLigand / hetero atomse2w9gA1
ECOD domains from experimental PDB structures interacting with ligand DB02338
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P0A017DB02338NDP2w9ge2w9gA1A:1-158
P0A017DB02338NDP3frde3frdX1X:1-157
P0A017DB02338NDP3free3freX1X:1-157
P0A017DB02338NDP3frfe3frfX1X:1-158
P0A017DB02338NDP3fy8e3fy8X1X:1-157
P0A017DB02338NDP3fyve3fyvX1X:1-158
P0A017DB02338NDP3fywe3fywX1X:1-158
P0A017DB02338NDP3i8ae3i8aX1X:1-157
P0A017DB02338NDP3lg4e3lg4A1A:1-157
P0A017DB02338NDP3lg4e3lg4B1B:1-157
P0A017DB02338NDP3sgye3sgyA1A:1-157
P0A017DB02338NDP3sgye3sgyB1B:1-157
P0A017DB02338NDP3sh2e3sh2A1A:1-157
P0A017DB02338NDP3sh2e3sh2B1B:1-157
P0A017DB02338NDP4xe6e4xe6X1X:1-157
P0A017DB02338NDP4xece4xecX1X:1-157