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5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine

P0A017 — Dihydrofolate reductase

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Attributes

UniProt ID
P0A017
Protein Name
Dihydrofolate reductase
Ligand Name
5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine
DrugBank ID
DB08741
PDB Ligand Accession
XCF
ChEMBL ID
CHEMBL1236788
PubChem ID
10247560
InChIKey
HWJPWWYTGBZDEG-AWEZNQCLSA-N
SMILES
COc1cc(c2c(c1OC)OC(C=C2)C3CC3)Cc4cnc(nc4N)N
Drug Action
n/a
Affinity Metrics
ic50:2.9 nM