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P0A017

folA — Dihydrofolate reductase

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Lists of molecules and drugs that interact with protein P0A017
DrugDomain DataDrugBank IDPDB LigandLigand NameChEMBLPubChemInChIKey
ExploreDB00440TOP
TRIMETHOPRIM
CHEMBL225578IEDVJHCEMCRBQM-UHFFFAOYSA-N
ExploreDB00563MTX
METHOTREXATE
CHEMBL34259126941FBOZXECLQNJBKD-ZDUSSCGKSA-N
ExploreDB02015DHF
DIHYDROFOLIC ACID
CHEMBL46294135398604;5280349;98792OZRNSSUDZOLUSN-LBPRGKRZSA-N
ExploreDB02338NDP
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
CHEMBL407009134821689;5884ACFIXJIJDZMPPO-NNYOXOHSSA-N
ExploreDB03461NAP
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
CHEMBL29506957525501;5885XJLXINKUBYWONI-NNYOXOHSSA-N
ExploreDB07938I2H
5-{[(2S)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl}pyrimidine-2,4-diamine
CHEMBL167330344141864HWJPWWYTGBZDEG-CQSZACIVSA-N
ExploreDB08234N22
5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine
CHEMBL48596125058133NNFDQABYXZBKRK-UHFFFAOYSA-N
ExploreDB08741XCF
5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine
CHEMBL123678810247560HWJPWWYTGBZDEG-AWEZNQCLSA-N
ExploreDB09462GOL
GLYCEROL
CHEMBL692753PEDCQBHIVMGVHV-UHFFFAOYSA-N
ExploreDB14511ACT
ACETATE ION
None175QTBSBXVTEAMEQO-UHFFFAOYSA-M
ExploreNone06U
6-ethyl-5-{(3R)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine
CHEMBL448357256955942KEPLBUUTAQCZOE-AWEZNQCLSA-N
ExploreNone06W
6-ethyl-5-{(3S)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine
CHEMBL528440056684135KEPLBUUTAQCZOE-CQSZACIVSA-N
ExploreNone0U5
(2E)-3-{5-[(2,4-diamino-6-propylpyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(2-methylprop-1-en-1-yl)phthalazin-2(1H)-yl]prop-2-en-1-one
None137347893FJDNNCPVIFOVAR-JYSHFMIGSA-N
ExploreNone0U6
(2E)-3-{5-[(2,4-diamino-6-ethylpyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(2-methylprop-1-en-1-yl)phthalazin-2(1H)-yl]prop-2-en-1-one
None137347894CWIYQEZJRSEBAE-CJZRDCOESA-N
ExploreNone1DN
7-[5,6-dimethoxy-2-(1,3-thiazol-2-yl)-1H-benzimidazol-1-yl]quinazoline-2,4-diamine
CHEMBL312801656595785WHHHBZDVDZWFFO-UHFFFAOYSA-N
ExploreNone1VM
7-[5,6-dimethyl-2-(1,3-thiazol-2-yl)-1H-benzimidazol-1-yl]quinazoline-2,4-diamine
CHEMBL312802146871716RLRIWYVVMLSWOC-UHFFFAOYSA-N
ExploreNone1VN
6-chloro-7-[5,6-dimethyl-2-(1,3-thiazol-2-yl)-1H-benzimidazol-1-yl]quinazoline-2,4-diamine
CHEMBL312801446898103WSVACSSBUCFLCD-UHFFFAOYSA-N
ExploreNone1VO
7-[5,6-dimethyl-2-(1,3-thiazol-4-yl)-1H-benzimidazol-1-yl]quinazoline-2,4-diamine
CHEMBL312802272771095LTVJIDPPWFXVJV-UHFFFAOYSA-N
ExploreNone52V
5-[(3S)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
CHEMBL57697644223989XZXVRKHUCSXVBM-CQSZACIVSA-N
ExploreNone5DR
6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine
CHEMBL127053352949513LBQMRSNKEUNXMT-UHFFFAOYSA-N
ExploreNoneEDO
1,2-ETHANEDIOL
CHEMBL457299174LYCAIKOWRPUZTN-UHFFFAOYSA-N
ExploreNoneG8J
6-ethyl-5-{(3S)-3-[2-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine
None133107903PPKWGSTVAQFAGZ-AWEZNQCLSA-N
ExploreNoneM23
7-(5-bromo-2-ethoxyphenyl)-6-methylquinazoline-2,4-diamine
CHEMBL181812453346509YCEDXTDKSNASDG-UHFFFAOYSA-N
ExploreNoneMMV
3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid
CHEMBL304003866563688VDGXZSSDCDPCRF-UHFFFAOYSA-N
ExploreNoneNDW
alpha-NADPH
None12313073ACFIXJIJDZMPPO-OPDHFMQKSA-N
ExploreNoneO71
(4-{6-[(2S)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-2H-1,3-benzodioxol-4-yl}phenyl)acetic acid
None139267762DFNOGZMANMBRCF-CQSZACIVSA-N
ExploreNoneOWG
3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-6,7-dimethoxy-1-(4-methoxyphenyl)-3,4-dihydrophthalazin-2(1H)-yl]propan-1-one
None146170547LGRHLMMHEUVVCK-PMERELPUSA-N
ExploreNoneOWJ
(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(3,5-dimethylphenyl)phthalazin-2(1H)-yl]prop-2-en-1-one
None146672960YJNMFIWPSJEFDR-MOGHOSLNSA-N
ExploreNoneOWM
(2E)-1-[(1R)-1-cyclopropyl-6,7-dimethoxyphthalazin-2(1H)-yl]-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}prop-2-en-1-one
None146170546WEOHMFQXNAIIAE-DIJOXEGBSA-N
ExploreNoneOWP
(2E)-1-[(1S)-1-benzylphthalazin-2(1H)-yl]-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}prop-2-en-1-one
None146170542OSCKDSROOCELQQ-JYSHFMIGSA-N
ExploreNoneOWS
(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(4-methylphenyl)phthalazin-2(1H)-yl]prop-2-en-1-one
None146170541YQJQZCMRSICFNE-DTQJJDMLSA-N
ExploreNoneOWV
(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(pentan-3-yl)-3,4-dihydrophthalazin-2(1H)-yl]prop-2-en-1-one
None146672961NVYBVAIPWQNGSG-GIPLCNRYSA-N
ExploreNoneQ11
7-(2-methoxyphenyl)quinazoline-2,4-diamine
CHEMBL181811353346505GZWYCJUKEDOCPW-UHFFFAOYSA-N
ExploreNoneQ12
7-(3,4-dimethoxyphenyl)-6-methylquinazoline-2,4-diamine
CHEMBL181811453346506UGJMRAQTQALEME-UHFFFAOYSA-N
ExploreNoneQ19
1-[3-(2,4-diamino-6-methylquinazolin-7-yl)phenyl]ethanone
CHEMBL181812053346507OCMSAMCSELNFPL-UHFFFAOYSA-N
ExploreNoneQ20
3-(2,4-diamino-6-methylquinazolin-7-yl)-4-ethoxybenzaldehyde
CHEMBL181812153346508BDVALXKNVWZHIQ-UHFFFAOYSA-N
ExploreNoneQ26
N-[3'-(2,4-diaminoquinazolin-7-yl)-4'-ethoxybiphenyl-3-yl]methanesulfonamide
CHEMBL181812753346510KBZJKRXRDPRBNM-UHFFFAOYSA-N
ExploreNoneQ27
7-(2-ethoxynaphthalen-1-yl)-6-methylquinazoline-2,4-diamine
CHEMBL181812853346511DYQBRXOQGFCHCN-UHFFFAOYSA-N
ExploreNoneR0Y
(2E)-1-[(1S)-1-cyclopropyl-6,7-dimethoxy-3,4-dihydrophthalazin-2(1H)-yl]-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}prop-2-en-1-one
None146170545WEOHMFQXNAIIAE-GJTXFRBNSA-N
ExploreNoneRAR
5-(3,4-dimethoxy-5-{(1E)-3-oxo-3-[(1S)-1-propylphthalazin-2(1H)-yl]prop-1-en-1-yl}benzyl)pyrimidine-2,4-diamine
CHEMBL123561742627761YGDVMSPWZQHNMB-NEQMZLFVSA-N
ExploreNoneU06
4-[3-[3-[2,4-bis(azanyl)-6-ethyl-pyrimidin-5-yl]prop-2-ynyl]-4-methoxy-phenyl]benzoic acid
CHEMBL3827532121493974KQGRJTMRAQWNLV-UHFFFAOYSA-N
ExploreNoneU75
4-[3-[3-[2,4-bis(azanyl)-6-ethyl-pyrimidin-5-yl]prop-2-ynyl]-5-methoxy-phenyl]benzoic acid
CHEMBL3828771123133740VLQRVOAJCWFFQG-UHFFFAOYSA-N
ExploreNoneUC9
4-{6-[(2S)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-2H-1,3-benzodioxol-4-yl}benzoic acid
None124081253NQHZOWBSMCFILX-CYBMUJFWSA-N
ExploreNoneXNP
Tricyclic NADPH
None137350166AJKICLDTLPZSPE-MTKBYBFRSA-N