N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
P0ABQ4 — Dihydrofolate reductase
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB11596
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand DB11596
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P0ABQ4 | DB11596 | 1jol | FFO | A | 161 | e1jolA1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| P0ABQ4 | DB11596 | 1jol | FFO | B | 361 | e1jolB1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| P0ABQ4 | DB11596 | 1jom | FFO | A | 161 | e1jomA1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |