DrugDomain

Attributes

UniProt ID

P0ABQ4

Protein Name

Dihydrofolate reductase

Ligand Name

FOLIC ACID

DrugBank ID

DB00158

PDB Ligand Accession

FOL

ChEMBL ID

n/a

PubChem ID

n/a

InChIKey

OVBPIULPVIDEAO-LBPRGKRZSA-N

SMILES

c1cc(ccc1C(=O)NC(CCC(=O)O)C(=O)O)NCc2cnc3c(n2)C(=O)N=C(N3)N

Drug Action

No data available

Affinity Metrics

No affinity data available

3D Structure

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Mol*

Structure: 1DYI

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Color Legend

Unassigned regionsLigand / hetero atomse1dyiA1e1dyiB1

ECOD domains from experimental PDB structures interacting with ligand DB00158

UniProt	DrugBank	PDB Ligand	PDB ID	ECOD Domain	Range Definition
P0ABQ4	DB00158	FOL	1dyi	e1dyiA1	A:1-159
P0ABQ4	DB00158	FOL	1dyi	e1dyiB1	B:1-159
P0ABQ4	DB00158	FOL	1ra2	e1ra2A1	A:1-159
P0ABQ4	DB00158	FOL	1ra8	e1ra8A1	A:1-159
P0ABQ4	DB00158	FOL	1rb2	e1rb2A1	A:1-159
P0ABQ4	DB00158	FOL	1rb2	e1rb2B1	B:1-159
P0ABQ4	DB00158	FOL	1rd7	e1rd7A1	A:1-159
P0ABQ4	DB00158	FOL	1rd7	e1rd7B1	B:1-159
P0ABQ4	DB00158	FOL	1re7	e1re7A1	A:1-159
P0ABQ4	DB00158	FOL	1re7	e1re7B1	B:1-159
P0ABQ4	DB00158	FOL	1rx2	e1rx2A1	A:1-159
P0ABQ4	DB00158	FOL	1rx7	e1rx7A1	A:1-159
P0ABQ4	DB00158	FOL	1rx8	e1rx8A1	A:1-159
P0ABQ4	DB00158	FOL	3ql3	e3ql3A1	A:1-159
P0ABQ4	DB00158	FOL	4ej1	e4ej1A1	A:1-159
P0ABQ4	DB00158	FOL	4ej1	e4ej1B1	B:1-159
P0ABQ4	DB00158	FOL	4fhb	e4fhbA1	A:1-159
P0ABQ4	DB00158	FOL	4i13	e4i13A1	A:1-159
P0ABQ4	DB00158	FOL	4i1n	e4i1nA1	A:1-159
P0ABQ4	DB00158	FOL	4kjj	e4kjjA1	A:1-159
P0ABQ4	DB00158	FOL	4kjk	e4kjkA1	A:1-159
P0ABQ4	DB00158	FOL	4kjl	e4kjlA1	A:1-160
P0ABQ4	DB00158	FOL	4nx6	e4nx6A1	A:1-159
P0ABQ4	DB00158	FOL	4nx7	e4nx7A1	A:1-159
P0ABQ4	DB00158	FOL	4x5f	e4x5fA1	A:1-159
P0ABQ4	DB00158	FOL	4x5f	e4x5fB1	B:0-159
P0ABQ4	DB00158	FOL	4x5g	e4x5gA1	A:1-159
P0ABQ4	DB00158	FOL	4x5g	e4x5gB1	B:0-159
P0ABQ4	DB00158	FOL	4x5h	e4x5hA1	A:1-159
P0ABQ4	DB00158	FOL	4x5i	e4x5iA1	A:1-159
P0ABQ4	DB00158	FOL	4x5j	e4x5jA1	A:1-159
P0ABQ4	DB00158	FOL	5sss	e5sssA1	A:1-159
P0ABQ4	DB00158	FOL	5sst	e5sstA1	A:1-159
P0ABQ4	DB00158	FOL	5ssu	e5ssuA1	A:1-159
P0ABQ4	DB00158	FOL	5ssv	e5ssvA1	A:1-159
P0ABQ4	DB00158	FOL	5ssw	e5sswA1	A:1-159
P0ABQ4	DB00158	FOL	5z6f	e5z6fA1	A:0-159
P0ABQ4	DB00158	FOL	5z6j	e5z6jA1	A:0-159
P0ABQ4	DB00158	FOL	5z6k	e5z6kA1	A:0-159
P0ABQ4	DB00158	FOL	5z6l	e5z6lA1	A:0-159
P0ABQ4	DB00158	FOL	5z6m	e5z6mA1	A:0-159
P0ABQ4	DB00158	FOL	7d3z	e7d3zA1	A:1-159
P0ABQ4	DB00158	FOL	7d49	e7d49A1	A:1-159
P0ABQ4	DB00158	FOL	7d4l	e7d4lA1	A:1-159
P0ABQ4	DB00158	FOL	7d4x	e7d4xA1	A:1-159
P0ABQ4	DB00158	FOL	7d6g	e7d6gA1	A:1-159
P0ABQ4	DB00158	FOL	7dfr	e7dfrA1	A:1-159
P0ABQ4	DB00158	FOL	7fpl	e7fplA1	A:1-159
P0ABQ4	DB00158	FOL	7fpm	e7fpmA1	A:1-159
P0ABQ4	DB00158	FOL	7fpn	e7fpnA1	A:1-159
P0ABQ4	DB00158	FOL	7fpo	e7fpoA1	A:1-159
P0ABQ4	DB00158	FOL	7fpp	e7fppA1	A:1-159
P0ABQ4	DB00158	FOL	7fpq	e7fpqA1	A:1-159
P0ABQ4	DB00158	FOL	7fpr	e7fprA1	A:1-159
P0ABQ4	DB00158	FOL	7fps	e7fpsA1	A:1-159
P0ABQ4	DB00158	FOL	7fpt	e7fptA1	A:1-159
P0ABQ4	DB00158	FOL	7fpu	e7fpuA1	A:1-159
P0ABQ4	DB00158	FOL	7fpv	e7fpvA1	A:1-159
P0ABQ4	DB00158	FOL	7fpw	e7fpwA1	A:1-159
P0ABQ4	DB00158	FOL	7fpx	e7fpxA1	A:1-159
P0ABQ4	DB00158	FOL	7fpy	e7fpyA1	A:1-159
P0ABQ4	DB00158	FOL	7fpz	e7fpzA1	A:1-159
P0ABQ4	DB00158	FOL	7fq0	e7fq0A1	A:1-159
P0ABQ4	DB00158	FOL	7fq1	e7fq1A1	A:1-159
P0ABQ4	DB00158	FOL	7fq2	e7fq2A1	A:1-159
P0ABQ4	DB00158	FOL	7fq3	e7fq3A1	A:1-159
P0ABQ4	DB00158	FOL	7fq4	e7fq4A1	A:1-159
P0ABQ4	DB00158	FOL	7fq5	e7fq5A1	A:1-159
P0ABQ4	DB00158	FOL	7fq6	e7fq6A1	A:1-159
P0ABQ4	DB00158	FOL	7fq7	e7fq7A1	A:1-159
P0ABQ4	DB00158	FOL	7fq8	e7fq8A1	A:1-159
P0ABQ4	DB00158	FOL	7fq9	e7fq9A1	A:1-159
P0ABQ4	DB00158	FOL	7fqa	e7fqaA1	A:1-159
P0ABQ4	DB00158	FOL	7fqb	e7fqbA1	A:1-159
P0ABQ4	DB00158	FOL	7fqc	e7fqcA1	A:1-159
P0ABQ4	DB00158	FOL	7fqd	e7fqdA1	A:1-159
P0ABQ4	DB00158	FOL	7fqe	e7fqeA1	A:1-159
P0ABQ4	DB00158	FOL	7fqf	e7fqfA1	A:1-159
P0ABQ4	DB00158	FOL	7fqg	e7fqgA1	A:1-159
P0ABQ4	DB00158	FOL	7lvc	e7lvcA1	A:1-159