NI-FE REDUCED ACTIVE CENTER

P0ACD8 — Hydrogenase-1 large chain

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand EJ2

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand EJ2

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P0ACD8	n/a	6fpi	EJ2	L	601	e6fpiL1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6fpi	EJ2	L	601	e6fpiL2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6fpi	EJ2	L	601	e6fpiL3	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P0ACD8	n/a	6fpi	EJ2	M	601	e6fpiM2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6fpi	EJ2	M	601	e6fpiM3	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P0ACD8	n/a	6fpi	EJ2	M	601	e6fpiM4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6fpw	EJ2	L	601	e6fpwL1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6fpw	EJ2	L	601	e6fpwL2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6fpw	EJ2	L	601	e6fpwL4	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P0ACD8	n/a	6fpw	EJ2	M	601	e6fpwM1	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P0ACD8	n/a	6fpw	EJ2	M	601	e6fpwM2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6fpw	EJ2	M	601	e6fpwM3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6g7r	EJ2	L	602	e6g7rL2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6g7r	EJ2	L	602	e6g7rL3	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P0ACD8	n/a	6g7r	EJ2	L	602	e6g7rL4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6g7r	EJ2	M	601	e6g7rM1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6g7r	EJ2	M	601	e6g7rM2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P0ACD8	n/a	6g7r	EJ2	M	601	e6g7rM4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6gal	EJ2	L	601	e6galL1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6gal	EJ2	L	601	e6galL2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6gal	EJ2	L	601	e6galL3	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P0ACD8	n/a	6gal	EJ2	M	602	e6galM2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
P0ACD8	n/a	6gal	EJ2	M	602	e6galM3	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P0ACD8	n/a	6gal	EJ2	M	602	e6galM4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases