DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
5,10-methylenetetrahydrofolate reductase
Ligand Name
N-[(5-{2-[(6R)-2-AMINO-4-OXO-3,4,5,6,7,8-HEXAHYDROPYRIDO[2,3-D]PYRIMIDIN-6-YL]ETHYL}-2-THIENYL)CARBONYL]-L-GLUTAMIC ACID
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
GQCXGHHHNACOGE-SKDRFNHKSA-N
SMILES
c1cc(sc1CCC2CC3=C(NC2)N=C(NC3=O)N)C(=O)NC(CCC(=O)O)C(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 2FMN
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Color Legend
Unassigned regionsLigand / hetero atomse2fmnA1e2fmnB1e2fmnC1
ECOD domains from experimental PDB structures interacting with ligand 4HF
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P0AEZ1n/a4HF2fmne2fmnA1A:3-295
P0AEZ1n/a4HF2fmne2fmnB1B:3-294
P0AEZ1n/a4HF2fmne2fmnC1C:21-296