THIAMINE DIPHOSPHATE

P0AFG8 — Pyruvate dehydrogenase E1 component

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand TPP

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand TPP

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P0AFG8	n/a	2iea	TPP	A	887	e2ieaA2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	PDH_E1_M
P0AFG8	n/a	2iea	TPP	A	887	e2ieaA3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
P0AFG8	n/a	2iea	TPP	A	887	e2ieaB2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	PDH_E1_M
P0AFG8	n/a	2iea	TPP	B	887	e2ieaA2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	PDH_E1_M
P0AFG8	n/a	2iea	TPP	B	887	e2ieaB1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
P0AFG8	n/a	2qta	TPP	A	887	e2qtaA4	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
P0AFG8	n/a	2qta	TPP	A	887	e2qtaB4	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	PDH_E1_M
P0AFG8	n/a	2qta	TPP	B	887	e2qtaA2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	PDH_E1_M
P0AFG8	n/a	2qta	TPP	B	887	e2qtaB2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N