THIAMINE DIPHOSPHATE

P0AFG9 — Pyruvate dehydrogenase E1 component

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand TPP

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand TPP

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P0AFG9	n/a	3lpl	TPP	A	887	e3lplA1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
P0AFG9	n/a	3lpl	TPP	A	887	e3lplB2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	PDH_E1_M
P0AFG9	n/a	3lpl	TPP	B	887	e3lplA4	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	PDH_E1_M
P0AFG9	n/a	3lpl	TPP	B	887	e3lplB4	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
P0AFG9	n/a	3lq2	TPP	A	887	e3lq2A2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	PDH_E1_M
P0AFG9	n/a	3lq2	TPP	A	887	e3lq2A4	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
P0AFG9	n/a	3lq2	TPP	A	887	e3lq2B2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	PDH_E1_M
P0AFG9	n/a	3lq2	TPP	B	887	e3lq2A2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	PDH_E1_M
P0AFG9	n/a	3lq2	TPP	B	887	e3lq2B1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
P0AFG9	n/a	3lq4	TPP	A	887	e3lq4A2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	PDH_E1_M
P0AFG9	n/a	3lq4	TPP	A	887	e3lq4A4	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
P0AFG9	n/a	3lq4	TPP	A	887	e3lq4B1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	PDH_E1_M
P0AFG9	n/a	3lq4	TPP	B	887	e3lq4A2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	PDH_E1_M
P0AFG9	n/a	3lq4	TPP	B	887	e3lq4B4	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N