1,2-ETHANEDIOL

P0C6U8 — Replicase polyprotein 1a

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand EDO

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand EDO

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P0C6U8	n/a	3vb3	EDO	A	406	e3vb3A1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6U8	n/a	3vb3	EDO	A	406	e3vb3A2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0C6U8	n/a	3vb3	EDO	B	402	e3vb3B1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6U8	n/a	3vb3	EDO	B	402	e3vb3B2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0C6U8	n/a	3vb4	EDO	A	403	e3vb4A1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6U8	n/a	3vb4	EDO	B	406	e3vb4B1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6U8	n/a	3vb4	EDO	B	406	e3vb4B2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0C6U8	n/a	3vb5	EDO	A	401	e3vb5A1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6U8	n/a	3vb5	EDO	B	402	e3vb5B1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6U8	n/a	3vb6	EDO	A	401	e3vb6A1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6U8	n/a	3vb7	EDO	A	401	e3vb7A2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0C6U8	n/a	3vb7	EDO	B	402	e3vb7B2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0C6U8	n/a	6xhn	EDO	A	9002	e6xhnA2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6U8	n/a	6xhn	EDO	A	9002	e6xhnB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6U8	n/a	6xho	EDO	A	9101	e6xhoA2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6U8	n/a	6xho	EDO	A	9101	e6xhoB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6U8	n/a	7lfv	EDO	A	2010	e7lfvA1	Cysteine proteinases-like	Cysteine proteinases	Cysteine proteinases	CoV_peptidase
P0C6U8	n/a	7lfv	EDO	B	413	e7lfvB1	Cysteine proteinases-like	Cysteine proteinases	Cysteine proteinases	CoV_peptidase
P0C6U8	n/a	7lfv	EDO	B	413	e7lfvB2	beta-Grasp	Ubiquitin-related	Ubiquitin-like	CoV_peptidase