(S)-N-benzyl-3-((S)-2-cinnamamido-3-phenylpropanamido)-2-oxo-4-((S)-2-oxopyrrolidin-3-yl)butanamide

P0C6X5 — Replicase polyprotein 1ab

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand D03

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand D03

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P0C6X5	n/a	6fv2	D03	A	402	e6fv2A1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6X5	n/a	6fv2	D03	A	402	e6fv2A2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0C6X5	n/a	6fv2	D03	B	402	e6fv2A1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6X5	n/a	6fv2	D03	B	402	e6fv2B1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6X5	n/a	6fv2	D03	B	402	e6fv2B2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0C6X5	n/a	6fv2	D03	B	402	e6fv2C2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6X5	n/a	6fv2	D03	C	402	e6fv2B1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0C6X5	n/a	6fv2	D03	C	402	e6fv2C1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0C6X5	n/a	6fv2	D03	C	402	e6fv2C2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30