Attributes
UniProt ID
Protein Name
Cys-loop ligand-gated ion channel
Ligand Name
Memantine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
BUGYDGFZZOZRHP-CDECOKDKSA-N
SMILES
CC12CC3CC(C1)(CC(C3)(C2)N)C
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 4TWD
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Color Legend
Unassigned regionsLigand / hetero atomse4twdA1e4twdA2e4twdB1e4twdB2e4twdC1e4twdC2e4twdD1e4twdD2e4twdE1e4twdE2e4twdF1e4twdF2e4twdG1e4twdG2e4twdH1e4twdH2e4twdI1e4twdI2e4twdJ1e4twdJ2
ECOD domains from experimental PDB structures interacting with ligand 377
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P0C7B7 | n/a | 377 | 4twd | e4twdA1 | A:200-317 |
| P0C7B7 | n/a | 377 | 4twd | e4twdA2 | A:11-199 |
| P0C7B7 | n/a | 377 | 4twd | e4twdB1 | B:200-317 |
| P0C7B7 | n/a | 377 | 4twd | e4twdB2 | B:11-199 |
| P0C7B7 | n/a | 377 | 4twd | e4twdC1 | C:200-317 |
| P0C7B7 | n/a | 377 | 4twd | e4twdC2 | C:11-199 |
| P0C7B7 | n/a | 377 | 4twd | e4twdD1 | D:200-317 |
| P0C7B7 | n/a | 377 | 4twd | e4twdD2 | D:11-199 |
| P0C7B7 | n/a | 377 | 4twd | e4twdE1 | E:200-317 |
| P0C7B7 | n/a | 377 | 4twd | e4twdE2 | E:11-199 |
| P0C7B7 | n/a | 377 | 4twd | e4twdF1 | F:200-317 |
| P0C7B7 | n/a | 377 | 4twd | e4twdF2 | F:11-199 |
| P0C7B7 | n/a | 377 | 4twd | e4twdG1 | G:200-317 |
| P0C7B7 | n/a | 377 | 4twd | e4twdG2 | G:11-199 |
| P0C7B7 | n/a | 377 | 4twd | e4twdH1 | H:200-317 |
| P0C7B7 | n/a | 377 | 4twd | e4twdH2 | H:11-199 |
| P0C7B7 | n/a | 377 | 4twd | e4twdI1 | I:200-317 |
| P0C7B7 | n/a | 377 | 4twd | e4twdI2 | I:11-199 |
| P0C7B7 | n/a | 377 | 4twd | e4twdJ1 | J:200-317 |
| P0C7B7 | n/a | 377 | 4twd | e4twdJ2 | J:11-199 |