(3~{S},3~{a}~{S},6~{a}~{R})-2-[(2~{S})-2-cyclohexyl-2-[2,2,2-tris(fluoranyl)ethanoylamino]ethanoyl]-~{N}-[(2~{S},3~{R})-4-(cyclopentylamino)-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]butan-2-yl]-3,3~{a},4,5,6,6~{a}-hexahydro-1~{H}-cyclopenta[c]pyrrole-3-carboxamide

P0DTC1 — Replicase polyprotein 1a

ECOD Domain Annotations

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P0DTC1	n/a	8ign	7ON	A	401	e8ignA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	n/a	8ign	7ON	A	401	e8ignA2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	n/a	8ign	7ON	A	401	e8ignB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	n/a	8ign	7ON	B	401	e8ignA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	n/a	8ign	7ON	B	401	e8ignA2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	n/a	8ign	7ON	B	401	e8ignB1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	n/a	8ign	7ON	B	401	e8ignB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30