6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione

P0DTC1 — Replicase polyprotein 1a

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB18834

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB18834

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P0DTC1	DB18834	7vu6	7YY	A	501	e7vu6A1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	7vu6	7YY	A	501	e7vu6A2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	7vu6	7YY	B	501	e7vu6B1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	7vu6	7YY	B	501	e7vu6B2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8h3g	7YY	A	401	e8h3gA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3g	7YY	A	401	e8h3gA2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8h3g	7YY	B	402	e8h3gA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3g	7YY	B	402	e8h3gB1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8h3g	7YY	B	402	e8h3gB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3k	7YY	A	401	e8h3kA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3k	7YY	A	401	e8h3kA2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8h3k	7YY	B	401	e8h3kA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3k	7YY	B	401	e8h3kB1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8h3k	7YY	B	401	e8h3kB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3l	7YY	A	401	e8h3lA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3l	7YY	A	401	e8h3lA2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8h3l	7YY	A	401	e8h3lB1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3l	7YY	B	401	e8h3lA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3l	7YY	B	401	e8h3lB1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3l	7YY	B	401	e8h3lB2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8h3l	7YY	C	401	e8h3lC1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8h3l	7YY	C	401	e8h3lC2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3l	7YY	C	401	e8h3lD1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3l	7YY	D	401	e8h3lC2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3l	7YY	D	401	e8h3lD1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8h3l	7YY	D	401	e8h3lD2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8hbk	7YY	A	401	e8hbkA1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8hbk	7YY	A	401	e8hbkA2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8hur	7YY	A	401	e8hurA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8hur	7YY	A	401	e8hurA2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8hur	7YY	B	401	e8hurB1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8hur	7YY	B	401	e8hurB2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8huv	7YY	A	401	e8huvA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8huv	7YY	A	401	e8huvA2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8huv	7YY	B	401	e8huvB1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8huv	7YY	B	401	e8huvB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8huw	7YY	A	401	e8huwA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8huw	7YY	A	401	e8huwA2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8huw	7YY	B	401	e8huwB1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8huw	7YY	B	401	e8huwB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8hux	7YY	A	401	e8huxA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB18834	8hux	7YY	A	401	e8huxA2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8hux	7YY	B	401	e8huxB1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB18834	8hux	7YY	B	401	e8huxB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30