DIMETHYL SULFOXIDE

P0DTC1 — Replicase polyprotein 1a

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB01093

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB01093

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P0DTC1	DB01093	7djr	DMS	A	404	e7djrA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7dk1	DMS	A	403	e7dk1A2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7dk1	DMS	B	404	e7dk1A2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7dk1	DMS	B	404	e7dk1B1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB01093	7dk1	DMS	B	404	e7dk1B2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nt1	DMS	A	503	e7nt1A2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nt1	DMS	A	503	e7nt1B1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nt1	DMS	A	503	e7nt1B2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB01093	7nt1	DMS	B	503	e7nt1B1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nt2	DMS	A	602	e7nt2A1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nt2	DMS	B	606	e7nt2A1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nt2	DMS	B	606	e7nt2B1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nt3	DMS	A	601	e7nt3A1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB01093	7nt3	DMS	A	601	e7nt3A2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nt3	DMS	A	601	e7nt3B1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nt3	DMS	B	704	e7nt3B1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7ntq	DMS	A	416	e7ntqA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7ntv	DMS	A	502	e7ntvA1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB01093	7ntv	DMS	A	502	e7ntvA2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7ntv	DMS	A	502	e7ntvB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7ntv	DMS	B	505	e7ntvB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7ntw	DMS	A	405	e7ntwA2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nuk	DMS	A	601	e7nukA1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB01093	7nuk	DMS	A	601	e7nukA2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nuk	DMS	A	601	e7nukB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nuk	DMS	B	703	e7nukB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nw2	DMS	A	405	e7nw2A1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7nw2	DMS	B	405	e7nw2B2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7p51	DMS	A	405	e7p51A1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7tvs	DMS	A	403	e7tvsA2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7tzj	DMS	A	406	e7tzjA2	Cysteine proteinases-like	Cysteine proteinases	Cysteine proteinases	CoV_peptidase
P0DTC1	DB01093	7tzj	DMS	B	407	e7tzjB1	Cysteine proteinases-like	Cysteine proteinases	Cysteine proteinases	CoV_peptidase
P0DTC1	DB01093	7vh8	DMS	A	402	e7vh8A2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB01093	7z4s	DMS	A	402	e7z4sA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	7z4s	DMS	A	402	e7z4sA2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB01093	7z4s	DMS	A	402	e7z4sB1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTC1	DB01093	8hht	DMS	A	403	e8hhtA1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTC1	DB01093	8hht	DMS	A	403	e8hhtA2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30