MAGNESIUM ION

P0DTD1 — Replicase polyprotein 1ab

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand MG

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand MG

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P0DTD1	n/a	6vww	MG	A	403	e6vwwA2	RNase A-like	EndoU-like	EndoU-like	CoV_NSP15_C
P0DTD1	n/a	6wtt	MG	A	407	e6wttA2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTD1	n/a	6wtt	MG	A	407	e6wttB1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTD1	n/a	6wtt	MG	B	403	e6wttB2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTD1	n/a	6wuu	MG	B	502	e6wuuB2	Cysteine proteinases-like	Cysteine proteinases	Cysteine proteinases	CoV_peptidase
P0DTD1	n/a	6wuu	MG	B	502	e6wuuD2	Cysteine proteinases-like	Cysteine proteinases	Cysteine proteinases	CoV_peptidase
P0DTD1	n/a	6wuu	MG	C	502	e6wuuC1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	CoV_peptidase
P0DTD1	n/a	6wuu	MG	C	502	e6wuuC2	Cysteine proteinases-like	Cysteine proteinases	Cysteine proteinases	CoV_peptidase
P0DTD1	n/a	6wuu	MG	D	503	e6wuuD1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	CoV_peptidase
P0DTD1	n/a	6wuu	MG	D	503	e6wuuD2	Cysteine proteinases-like	Cysteine proteinases	Cysteine proteinases	CoV_peptidase
P0DTD1	n/a	6xez	MG	A	1003	e6xezA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	6xez	MG	E	706	e6xezE2	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	6xez	MG	F	1005	e6xezF4	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	6xqb	MG	A	1003	e6xqbA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	6ywk	MG	C	201	e6ywkC1	Macro domain-like	Macro domain-like	Macro domain-like	Macro
P0DTD1	n/a	6ywk	MG	E	201	e6ywkE1	Macro domain-like	Macro domain-like	Macro domain-like	Macro
P0DTD1	n/a	6ywl	MG	C	202	e6ywlC1	Macro domain-like	Macro domain-like	Macro domain-like	Macro
P0DTD1	n/a	6ywl	MG	E	202	e6ywlE1	Macro domain-like	Macro domain-like	Macro domain-like	Macro
P0DTD1	n/a	6ywm	MG	B	201	e6ywmB1	Macro domain-like	Macro domain-like	Macro domain-like	Macro
P0DTD1	n/a	6ywm	MG	C	202	e6ywmC1	Macro domain-like	Macro domain-like	Macro domain-like	Macro
P0DTD1	n/a	7aap	MG	A	1004	e7aapA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7aap	MG	P	101	e7aapA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7bf3	MG	B	201	e7bf3B1	Macro domain-like	Macro domain-like	Macro domain-like	Macro
P0DTD1	n/a	7bf3	MG	C	201	e7bf3C1	Macro domain-like	Macro domain-like	Macro domain-like	Macro
P0DTD1	n/a	7bf5	MG	A	201	e7bf5A1	Macro domain-like	Macro domain-like	Macro domain-like	Macro
P0DTD1	n/a	7bf5	MG	A	201	e7bf5E1	Macro domain-like	Macro domain-like	Macro domain-like	Macro
P0DTD1	n/a	7bf5	MG	C	201	e7bf5C1	Macro domain-like	Macro domain-like	Macro domain-like	Macro
P0DTD1	n/a	7bf5	MG	E	201	e7bf5E1	Macro domain-like	Macro domain-like	Macro domain-like	Macro
P0DTD1	n/a	7bv2	MG	A	1005	e7bv2A1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7cyq	MG	A	1004	e7cyqA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7cyq	MG	A	1004	e7cyqG1	cradle loop barrel	RIFT-related	Phage tail proteins	CoV_NSP9
P0DTD1	n/a	7dfg	MG	A	1008	e7dfgA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7dfh	MG	A	1005	e7dfhA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7diy	MG	B	303	e7diyB1	Ribonuclease H-like	Ribonuclease H-like	Ribonuclease H-like	CoV_ExoN
P0DTD1	n/a	7doi	MG	A	1007	e7doiA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7dok	MG	A	1006	e7dokA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7dok	MG	P	1202	e7dokA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7ed5	MG	A	1007	e7ed5A1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7egq	MG	K	604	e7egqK1	Ribonuclease H-like	Ribonuclease H-like	Ribonuclease H-like	CoV_ExoN
P0DTD1	n/a	7egq	MG	X	603	e7egqX1	Ribonuclease H-like	Ribonuclease H-like	Ribonuclease H-like	CoV_ExoN
P0DTD1	n/a	7eiz	MG	K	604	e7eizK1	Ribonuclease H-like	Ribonuclease H-like	Ribonuclease H-like	CoV_ExoN
P0DTD1	n/a	7jyy	MG	A	7102	e7jyyA1	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	CoV_Methyltr_2
P0DTD1	n/a	7jyy	MG	C	7102	e7jyyC1	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	CoV_Methyltr_2
P0DTD1	n/a	7krn	MG	A	1003	e7krnA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7krn	MG	E	705	e7krnE2	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7krn	MG	E	705	e7krnE4	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_12
P0DTD1	n/a	7kro	MG	A	1003	e7kroA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7kro	MG	E	705	e7kroE1	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7kro	MG	E	705	e7kroE6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_12
P0DTD1	n/a	7kro	MG	F	1004	e7kroF5	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7kro	MG	F	1004	e7kroF6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_12
P0DTD1	n/a	7krp	MG	A	1003	e7krpA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7l6t	MG	A	7101	e7l6tA1	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	CoV_Methyltr_2
P0DTD1	n/a	7l6t	MG	C	101	e7l6tA1	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	CoV_Methyltr_2
P0DTD1	n/a	7lw3	MG	A	702	e7lw3A1	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	CoV_Methyltr_2
P0DTD1	n/a	7mc6	MG	A	311	e7mc6A1	Ribonuclease H-like	Ribonuclease H-like	Ribonuclease H-like	CoV_ExoN
P0DTD1	n/a	7n0c	MG	B	602	e7n0cB1	Ribonuclease H-like	Ribonuclease H-like	Ribonuclease H-like	CoV_ExoN
P0DTD1	n/a	7n0d	MG	B	602	e7n0dB1	Ribonuclease H-like	Ribonuclease H-like	Ribonuclease H-like	CoV_ExoN
P0DTD1	n/a	7n0d	MG	D	601	e7n0dD1	Ribonuclease H-like	Ribonuclease H-like	Ribonuclease H-like	CoV_ExoN
P0DTD1	n/a	7n0d	MG	F	602	e7n0dF1	Ribonuclease H-like	Ribonuclease H-like	Ribonuclease H-like	CoV_ExoN
P0DTD1	n/a	7n0d	MG	H	702	e7n0dH1	Ribonuclease H-like	Ribonuclease H-like	Ribonuclease H-like	CoV_ExoN
P0DTD1	n/a	7nn0	MG	A	705	e7nn0A4	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_12
P0DTD1	n/a	7nn0	MG	A	705	e7nn0A5	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7rdx	MG	A	1003	e7rdxA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7rdx	MG	E	705	e7rdxE3	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_12
P0DTD1	n/a	7rdx	MG	E	705	e7rdxE6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7rdx	MG	F	1004	e7rdxF6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7rdy	MG	A	1003	e7rdyA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7rdy	MG	E	1004	e7rdyE3	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_12
P0DTD1	n/a	7rdy	MG	E	1004	e7rdyE6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7rdy	MG	F	1004	e7rdyF6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7rdz	MG	A	2002	e7rdzA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7re0	MG	A	2002	e7re0A1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7re0	MG	E	1004	e7re0E6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7re0	MG	F	1004	e7re0F6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7re1	MG	A	1003	e7re1A1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7re1	MG	E	705	e7re1E3	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_12
P0DTD1	n/a	7re1	MG	E	705	e7re1E6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7re1	MG	F	1004	e7re1F6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7re2	MG	A	1003	e7re2A1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7re2	MG	E	705	e7re2E3	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_12
P0DTD1	n/a	7re2	MG	E	705	e7re2E6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7re3	MG	A	2002	e7re3A1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7re3	MG	E	705	e7re3E3	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_12
P0DTD1	n/a	7re3	MG	E	705	e7re3E6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7re3	MG	F	1004	e7re3F6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7re3	MG	G	2002	e7re3G1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7re3	MG	K	705	e7re3K3	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_12
P0DTD1	n/a	7re3	MG	K	705	e7re3K6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7re3	MG	L	1004	e7re3L6	P-loop domains-like	P-loop domains-related	P-loop containing nucleoside triphosphate hydrolases	AAA_11
P0DTD1	n/a	7uo4	MG	A	1002	e7uo4A1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7uo7	MG	A	1002	e7uo7A1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7uo9	MG	A	1003	e7uo9A1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7uob	MG	A	1005	e7uobA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7uoe	MG	A	1004	e7uoeA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	7wqk	MG	A	400	e7wqkA1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTD1	n/a	7wqk	MG	A	400	e7wqkA2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTD1	n/a	8gwe	MG	A	1004	e8gweA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	8gwg	MG	A	1004	e8gwgA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	8sq9	MG	A	1007	e8sq9A1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	8sq9	MG	A	1007	e8sq9G1	cradle loop barrel	RIFT-related	Phage tail proteins	CoV_NSP9
P0DTD1	n/a	8sqj	MG	A	1002	e8sqjA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N
P0DTD1	n/a	8sqj	MG	A	1002	e8sqjG1	cradle loop barrel	RIFT-related	Phage tail proteins	CoV_NSP9
P0DTD1	n/a	8sqk	MG	A	1005	e8sqkA1	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_1,CoV_RPol_N