methyl N-[(4S)-6-chloro-4-[(isoquinolin-4-yl)carbamoyl]-3,4-dihydroisoquinoline-2(1H)-sulfonyl]-N-methylglycinate
P0DTD1 — Replicase polyprotein 1ab
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand R9I
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand R9I
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P0DTD1 | n/a | 7gli | R9I | A | 406 | e7gliA1 | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Peptidase_C30 |
| P0DTD1 | n/a | 7gli | R9I | A | 406 | e7gliA2 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| P0DTD1 | n/a | 7gli | R9I | A | 406 | e7gliB1 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| P0DTD1 | n/a | 7gli | R9I | B | 403 | e7gliA2 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| P0DTD1 | n/a | 7gli | R9I | B | 403 | e7gliB1 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| P0DTD1 | n/a | 7gli | R9I | B | 403 | e7gliB2 | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Peptidase_C30 |