(4S)-6-chloro-2-[2-(methylamino)-2-oxoethyl]-N-(5-methylisoquinolin-4-yl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
P0DTD1 — Replicase polyprotein 1ab
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand RJF
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand RJF
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P0DTD1 | n/a | 7gmf | RJF | A | 408 | e7gmfA1 | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Peptidase_C30 |
| P0DTD1 | n/a | 7gmf | RJF | A | 408 | e7gmfA2 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| P0DTD1 | n/a | 7gmf | RJF | A | 408 | e7gmfB1 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| P0DTD1 | n/a | 7gmf | RJF | B | 405 | e7gmfA2 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| P0DTD1 | n/a | 7gmf | RJF | B | 405 | e7gmfB1 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| P0DTD1 | n/a | 7gmf | RJF | B | 405 | e7gmfB2 | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Peptidase_C30 |