Attributes
UniProt ID
Protein Name
Replicase polyprotein 1ab
Ligand Name
2-[(3'S)-6-chloro-1'-(isoquinolin-4-yl)-2'-oxo-1H-spiro[isoquinoline-4,3'-pyrrolidin]-2(3H)-yl]-N-methylacetamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KZHDXVVSRJEQJU-XMMPIXPASA-N
SMILES
CNC(=O)CN1Cc2ccc(cc2C3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 7GMV
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Color Legend
Unassigned regionsLigand / hetero atomse7gmvA1e7gmvA2e7gmvB1e7gmvB2
ECOD domains from experimental PDB structures interacting with ligand RPZ
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P0DTD1 | n/a | RPZ | 7gmv | e7gmvA1 | A:187-305 |
| P0DTD1 | n/a | RPZ | 7gmv | e7gmvA2 | A:1-186 |
| P0DTD1 | n/a | RPZ | 7gmv | e7gmvB1 | B:1-186 |
| P0DTD1 | n/a | RPZ | 7gmv | e7gmvB2 | B:187-305 |
| P0DTD1 | n/a | RPZ | 7gn8 | e7gn8A1 | A:187-305 |
| P0DTD1 | n/a | RPZ | 7gn8 | e7gn8A2 | A:1-186 |
| P0DTD1 | n/a | RPZ | 7gn8 | e7gn8B1 | B:187-305 |
| P0DTD1 | n/a | RPZ | 7gn8 | e7gn8B2 | B:1-186 |