DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Replicase polyprotein 1ab
Ligand Name
1-{[(3'S)-6-chloro-1'-{6-[2-(dimethylamino)ethoxy]isoquinolin-4-yl}-2'-oxo-1H-spiro[isoquinoline-4,3'-pyrrolidine]-2(3H)-sulfonyl]methyl}cyclopropane-1-carbonitrile
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
FLBSSPVVUCLCOS-SSEXGKCCSA-N
SMILES
CN(C)CCOc1ccc2cncc(c2c1)N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 7GNH
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Color Legend
Unassigned regionsLigand / hetero atomse7gnhA1e7gnhA2e7gnhB1e7gnhB2
ECOD domains from experimental PDB structures interacting with ligand RYB
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P0DTD1n/aRYB7gnhe7gnhA1A:187-300
P0DTD1n/aRYB7gnhe7gnhA2A:1-186
P0DTD1n/aRYB7gnhe7gnhB1B:1-186
P0DTD1n/aRYB7gnhe7gnhB2B:187-305