Attributes
UniProt ID
Protein Name
Replicase polyprotein 1ab
Ligand Name
1-[(3'S)-6-chloro-1'-(isoquinolin-4-yl)-1,2'-dioxo-1H-spiro[isoquinoline-4,3'-pyrrolidin]-2(3H)-yl]-N-methylcyclopropane-1-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
FLEUPKADUSMVNQ-RUZDIDTESA-N
SMILES
CNC(=O)C1(CC1)N2CC3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 7GNJ
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Color Legend
Unassigned regionsLigand / hetero atomse7gnjA1e7gnjA2e7gnjB1e7gnjB2
ECOD domains from experimental PDB structures interacting with ligand RZU
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P0DTD1 | n/a | RZU | 7gnj | e7gnjA1 | A:187-306 |
| P0DTD1 | n/a | RZU | 7gnj | e7gnjA2 | A:1-186 |
| P0DTD1 | n/a | RZU | 7gnj | e7gnjB1 | B:187-305 |
| P0DTD1 | n/a | RZU | 7gnj | e7gnjB2 | B:1-186 |
| P0DTD1 | n/a | RZU | 7gnr | e7gnrA1 | A:187-306 |
| P0DTD1 | n/a | RZU | 7gnr | e7gnrA2 | A:1-186 |
| P0DTD1 | n/a | RZU | 7gnr | e7gnrB1 | B:1-186 |
| P0DTD1 | n/a | RZU | 7gnr | e7gnrB2 | B:187-305 |