2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL

P0DTD1 — Replicase polyprotein 1ab

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB03754

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB03754

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P0DTD1	DB03754	6wlc	TRS	A	402	e6wlcA2	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	n/a
P0DTD1	DB03754	6wlc	TRS	B	402	e6wlcB2	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	n/a
P0DTD1	DB03754	7r2v	TRS	A	603	e7r2vA2	Ribonuclease H-like	Ribonuclease H-like	Ribonuclease H-like	CoV_ExoN
P0DTD1	DB03754	8drz	TRS	A	406	e8drzA1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTD1	DB03754	8drz	TRS	B	403	e8drzB1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTD1	DB03754	8drz	TRS	C	403	e8drzC2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTD1	DB03754	8drz	TRS	E	401	e8drzE2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTD1	DB03754	8drz	TRS	F	405	e8drzF1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTD1	DB03754	8drz	TRS	F	405	e8drzF2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
P0DTD1	DB03754	8drz	TRS	G	402	e8drzG1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
P0DTD1	DB03754	8u2x	TRS	A	401	e8u2xA2	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	n/a
P0DTD1	DB03754	8u2x	TRS	B	401	e8u2xB2	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	n/a