N-{(2S,3R)-4-(benzylamino)-3-hydroxy-4-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}-N~2~-[(benzyloxy)carbonyl]-L-leucinamide
P0DTD1 — Replicase polyprotein 1ab
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand VR4
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand VR4
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P0DTD1 | n/a | 7k0f | VR4 | A | 401 | e7k0fA1 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| P0DTD1 | n/a | 7k0f | VR4 | A | 401 | e7k0fA2 | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Peptidase_C30 |
| P0DTD1 | n/a | 7k0f | VR4 | B | 401 | e7k0fB1 | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Peptidase_C30 |
| P0DTD1 | n/a | 7k0f | VR4 | B | 401 | e7k0fB2 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |